Abstract: 【Purpose/significance】The rise of Internet information technology has driven the development of regional economy, which also produces a lot of economic information. As a new force to transform the Internet, blockchain will bring great changes to information resource sharing activities and information service institutions.【Method/process】Blockchain technology is a new technology. It has the characteristics of openness, transparency and non tampering by building the system trust mechanism in a decentralized way. Taking this technology as the key to realize the security of system data storage and use, this paper designs the framework of regional economic information sharing based on blockchain technology.【Result/conclusion】The block chain technology is used to set up the double chain storage mode of regional economic information, and P2P is used to realize the regional economic information sharing.【Innovation/limitation】In the following research, this paper will shift from theoretical research to practical application. There are still some problems in blockchain and its technology, and many difficulties need to be overcome to realize regional economic information sharing based on blockchain.