Abstract: 【Purpose/significance】In the background of "new infrastructure", the promotion of information infrastructure construction can stimulate the integration of informationization and industrialization.【Method/process】Based on the provincial data from 2003 to 2018, we explore the dynamic influence of the information infrastructure and its interaction with urbanization on the integration of in⁃ formationization and industrialization through the SYS-GMM dynamic panel data model .【Result/conclusion】Information infrastruc⁃ ture and its integration with urbanization have a positive effect on the integration of informationization and industrialization on a sus⁃ tained basis. The role of information infrastructure and its integration with urbanization in promoting the integration of informationiza⁃ tion and industrialization shows an increasing trend, and there are significant regional differences in the role of information infrastruc⁃ ture and its integration with urbanization in promoting the integration of informationization and industrialization.【Innovation/limita⁃ tion】The main contribution of this paper is to empirically analyze the impact of information infrastructure on the integration of informa⁃ tionization and industrialization. The main limitation is that there are many factors affecting the integration. Thus, future research can examine the possible effect of other factors such as R&D intensity and consumption level.