Research status and progress on exosomes in the diagnosis and treatment of malignant glioma
Tang Shaohua,Yin Jun,Wang Weidong,Lang Jinyi
Southwest Medical University,Luzhou 646000,China (Tang SH);Department of Radiotherapy,Sichuan Cancer Hospital& Institute,Sichuan Cancer Center,School of Medicine,University of Electronic Science and Technology of China,Chengdu 610041,China (Tang SH,Yin J,Wang WD,Lang JY)
Abstract： In recent years, exosomes has gradually captivated widespread attention. It plays a crucial role in the proliferation, differentiation and metastasis of malignant tumors. As nanosized vesicles,exosomes can penetrate through the blood-brain barrier. Thus,exosomes may be a novel tool for the diagnosis and treatment of malignant glioma. In this paper, 57 relevant literatures were reviewed to summarize the research status and progress on the role of exosomes in the incidence, progression, liquid biopsy, prognosis evaluation and clinical therapy of malignant glioma.
Tang Shaohua,Yin Jun,Wang Weidong et al. Research status and progress on exosomes in the diagnosis and treatment of malignant glioma[J]. Chinese Journal of Radiation Oncology, 2018, 27(4): 425-429.
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