This paper puts neutral paper as the carrier and chooses several common handwriting materials as researched objects such as pigment ink, carbon ink, pen inks and printing ink. Various file-writing samples with different pigments are made by distilled water, hydrogen peroxide-ether, and hydrogen peroxide-ether plus oxalic acid/ethanol plus among/methanol decontamination reinforcement. Aiming to probe into the influences of peroxide-ether decontamination to the Durability of file-writing, some tests are used such as thermosenescence,UV-light aging,acid proofing,alkali resistivity,oxidation resistance and etc. The test draws the conclusion that the hydrogen peroxide-ether decontamination on paper the handwriting has bigger effect; the combination of oxidation decontamination and strengthening protection would improve the durability of the file.