头颈部肿瘤大分割放疗的研究进展及在新冠疫情中的临床价值

doi:10.3760/cma.j.cn113030-20210715-00266

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Abstract Radiotherapy is an essential part of comprehensive treatment, as well as a radical treatment for head and neck cancer (HNC). The COVID-19has continued so far, imposing a great impact on cancer care. Since conventional fractionated radiotherapy (CFRT, 2Gy/F) requires as long as more than six weeks of treatment time, a huge challenge for epidemic control is created for both hospitals and patients. Hypofractionated radiotherapy (Hypo-RT) may be more suitable than CFRT for patients during pandemic by increasing the fraction size, thus reducing fraction number and treatment duration. Early studies have explored the application of Hypo-RT in HNC in palliative setting, which partially proved its safety and effectiveness. Recently, the efforts have been made in definitive treatment using hypofractionated regimen, as well as its combination with systemic treatment and immunotherapy. Indeed, regarding the pandemic of COVID-19, Hypo-RT has been recommended by several expert consensus in the HNC. In this review, relevant research progress was summarized and clinical implication of Hypo-RT in COVID-19 pandemic era was discussed.

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	Articles by authors
	Shao Shilong
	Li Churong
	Chen Sihao
	He Shanshan
	Zhong Zuxian
	Wang Dan
	Feng Mei
	Zhang Peng
	Zhang Shichuan

Key words： COVID-19 Head and neck neoplasms Hypofractionated radiotherapy

Received: 15 July 2021

Fund:National Natural Science Foundation of China (81771921)

Corresponding Authors: Zhang Shichuan, Email:zhangsc65@hotmail.com

Cite this article:

Shao Shilong,Li Churong,Chen Sihao et al. Hypofractionated radiotherapy of head and neck cancer:research progress and clinical value in COVID-19 pandemic[J]. Chinese Journal of Radiation Oncology, 2022, 31(6): 569-573.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.cn113030-20210715-00266 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2022/V31/I6/569

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