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宫颈癌九野均分与角度优化IMRT计划剂量学比较
庞廷田, 杨波, 邱杰, 张福泉
100730 北京协和医学院 中国医学科学院北京协和医院放疗科
Dosimetric comparison of Cervix uteri irradiation with 9 equal spaced fields IMRT and beam angle optimized IMRT
Pang Tingtian, yang Bo,Zhang Fu-quan,Qiu Jie
Department of Radiotherapy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China.
Abstract:Objective To study the dosimetry characteristics of 9 equal spaced fields and 9 fields with beam angle optimization (BAO) process for cervix uteri. Methods 12 cervix uteri cancer patients CT Images were transferred into Eclipse planning system. Each patient, the 9 equal spaced fields and 9 fields by BAO process were IMRT plan designed with the same CT image. Make a evaluation of dose distribution for target volume and OARs, and paired t test for them. Results Comparing to 9 equal spaced fields IMRT plan, the quality of 9 fields IMRT plan with BAO process the the PTV V95% was 99.31% vs 99.42%,P=0.020, at the same time V105%,V110%,Dmax,Dmean got 60.54% vs 47.92%,P=0.013;7.14% vs 0.37%,P=0.000;56.62 Gy vs 55.47 Gy,P=0.000;53.29 Gy vs 52.72 Gy,P=0.000, the CI and HI was 0.85 vs 0.89,P=0.000;0.10 vs 0.13,P=0.000.For organs at risk, bladder V40 was increased by 4.7%(P=0.013);the D40 of rectum was 0.5 Gy higher (P=0.004);the small bowel′s DVH showed that V40 and Dmax increased by 0.6%(P=0.015) and 1.4 Gy (P=0.000), Dmean of bone marrow were raised separately by 1.3 Gy (P=0.000),the spinal cord′s dose D0.1 cm3 was also increased by 2.0 Gy (P=0.000). Conclusion The quality of 9 equal spaced fields IMRT plan will be better than those achieved by BAO process optimized plans.
Pang Tingtian,yang Bo,Zhang Fu-quan et al. Dosimetric comparison of Cervix uteri irradiation with 9 equal spaced fields IMRT and beam angle optimized IMRT[J]. Chinese Journal of Radiation Oncology, 2014, 23(3): 262-264.
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