[an error occurred while processing this directive]|[an error occurred while processing this directive]
发泡胶与乳腺托架在乳腺癌保乳术后IMRT中固定精度比较
房建南 , 马玉家 , 石俊田 , 黄江华 , 吴秀秀 , 马爽 , 陈锦树 , 黄晓波
中山大学孙逸仙纪念医院肿瘤放疗科,广州 510120
Comparison of imbolization accuracy between styrofoam and breast carrier in intensity-modulated radiotherapy after breast conservative surgery for breast cancer patients
Fang Jianhui, Ma Yujia, Shi Juntian, Huang Jianghua, Wu Xiuxiu, Ma Shuang, Cheng Jinshu, Huang Xiaobo
Department of Radiation Oncology,Sun Yat Sian Memorial Hospital,Sun Yat-sen University,Guangzhou 510120,China
Abstract：Objective To investigate the difference of styrofoam and breast carrier in postposition fixation of intensity-modulated radiotherapy after breast conservative surgery for breast cancer patients.Methods From February 2018 to August 2018,tweenty-four patients with breast cancer in Sun Yet-Sen Memorial Hospital of Sun Yet-sen University were selected for this study, who underwent hypofactionationed radiotherapy after breast conservative surgery with total dose 42.56 Gy/16Fractions. They were randomized into styrofoam test group and breastcarrier control group. Cone beam CT as used to record the positioning error under the directions of left and right (x),head and foot (y),abdomen and back (y) within two groups at the first,third,fifth,seventh, eleventh time before irradiation. Furthermore,the PTV extension margin was calculated and the positioning time of two groups was recorded. Two sets of pendulum errors were analyzed by independent sample T-test,and the outspread value of inter-fractional set up error of the PTV was calculated.Results The errors of the test group and the control group in the direction of x,y,z were as follows:(2.36±1.89) and (2.56±2.05) mm (P=0.49),(1.76±1.78) and (3.28±2.79) mm (P<0.05),(1.47±1.49) and (1.73±1.81) mm (P=0.28).The extension values of inter-fractional set up error of CTV to PTV were 2.97,2.92,2.21 mm and 3.41,4.09,2.59 mm respectively. The time of single positioning was (3.4±1.1) and (5.5 ±3.1) min respectively (P=0.01).Conclusions Styrofoam has better positioning accuracy and efficiency compared with breast carrier.
Fang Jianhui,Ma Yujia,Shi Juntian et al. Comparison of imbolization accuracy between styrofoam and breast carrier in intensity-modulated radiotherapy after breast conservative surgery for breast cancer patients[J]. Chinese Journal of Radiation Oncology, 2019, 28(5): 369-372.
[1]Ebctcg E B C T,S D,P M,et al. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death:meta-analysis of individual patient data for10 801 women in 17 randomised trials[J].Lancet,2012,23(3):266-267.DOI:10.1016/S0140-6736(11)61629-2. [2]Maaren MCV,Munck LD,Bock GHD,et al.10 year survival after breast-conserving surgery plus radiotherapy compared with mastectomy in early breast cancer in the Netherlands:a population-based study[J].Lancet Oncol,2016,17(8):1158-1170.DOI:10.1016/S1470-2045(16)30067-5. [3]Lancellotti P,Suter T M,López-Fernández T,et al. Cardio-oncology services:rationale,organization,and implementation[J].Eur Heart J,2018,00(1):1-8.DOI:10.1093/eurheartj/ehy453. [4]黄晓波,蒋国樑,陈佳艺,等.乳腺癌调强放射治疗和常规切线野治疗的三维剂量学研究[J].癌症进展,2006,25(7):855-860.DOI:10.3321/j.issn:1000-467X.2006.07.013. Huang XB,Jiang GL,Chen JY,et al. Three-dimensional dosimetry of breast cancer intensity modulated radiotherapy and conventional tangent field therapy[J].Oncol rog,2006,25(7):855-860.DOI:10.3321/j.issn:1000-467X.2006.07.013. [5]Herk MV.Errors and margins in radiotherapy[J].Sem Radiat Oncol,2004,14(1):52-64.DOI:10.1053/j.semradonc.2003.10.003. [6]Hodapp N.The ICRU report 83:prescribing,recording and reporting photon-beam intensity-modulated radiation therapy (IMRT)][J].Strahlenther Onkol,2012,188(1):97-99.DOI:10.1007/s00066-011-0015-x. [7]黄晓波,陈佳艺,蒋国樑,等.乳腺癌全乳切线野照射中靶区移动影响因素的研究[J].中华放射肿瘤学杂志,2006,15(6):453-456.DOI:10.3760/j.issn:1004-4221.2006.06.006. Huang XB,Chen JY,Jiang GL,et al. Study on the factors influencing the movement of target area in breast cancer whole milk tangent field[J].Chin J Radiat Oncol,2006,15(6):453-456.DOI:10.3760/j.issn:1004-4221.2006.06.006. [8]许森奎,姚文燕,胡江,等.鼻咽癌发泡胶个体化塑形与标准化头枕放疗体位固定精确度比较[J].中华放射肿瘤学杂志,2015,24(2):196-199.DOI:10.3760/cma.j.issn.1004-4221.2015.02.022. Xu SK,Yao WY,Hu J,et al. Comparison of fixed accuracy between individualized shaping of nasopharyngeal carcinoma and standardized headrest radiotherapy[J].Chin J Radiat Oncol,2015,24(2):196-199.DOI:10.3760/cma.j.issn.1004-4221.2015.02.022. [9]张英婷,刘炳忠,陈文芬,等.聚氨酯发泡胶结合翼板个体化塑形与负压真空袋固定肺癌放疗摆位精度比较[J].中华放射肿瘤学杂志,2018,27(3):299-302.DOI:10.3760/cma.j.issn.1004-4221.2018.03.014. Zhang YT,Liu BZ,Chen WF,et al. Comparison of radiotherapy accuracy of polyurethane foaming glue combined with individual shaping of wing plate and negative pressure vacuum bag fixation for lung cancer[J].Chin J Radiat Oncol,2018,27(3):299-302.DOI:10.3760/cma.j.issn.1004-4221.2018.03.014. [10]周常锋,石俊田,马玉家,等.乳腺癌保乳根治术后精确放疗体位固定的新方法[J].广东医学,2018,39(1):99-101.DOI:10.13820/j.cnki.gdyx.2018.s1.034. Zhou CF,Shi JT,Ma YJ,et al. A new method for accurate radiotherapy and position fixation of breast cancer after radical mastectomy[J].Guangdong Med,2018,39(1):99-101.DOI:10.13820/j.cnki.gdyx.2018.s1.034. [11]吴传锋,吴锦昌,顾科,等.水固化头枕对提高乳腺托架固定下乳腺癌放疗锁骨上野摆位准确性的研究[J].中华放射医学与防护杂志,2017,37(9):686-689.DOI:10.3760/cma.j.issn.0254-5098.2017.09.009. Wu CF,Wu JC,Gu K,et al. Study on the accuracy of water-cured headrest in improving the placement of clavicle Ueno in breast cancer under the fixation of breast bracket[J].Chin J Radiol Med Protect,2017,37(9):686-689.DOI:10.3760/cma.j.issn.0254-5098.2017.09.009. [12]Strydhorst JH,Caudrelier JM,Clark BG,et al. Evaluation of a thermoplastic immobilization system for breast and chest wall radiation therapy[J].Med Dosim,2011,36(1):81-84.DOI:10.1016/j.meddos.2010.01.001. [13]Agostinelli S,Garelli S,Bellini A,et al. Helical Tomotherapy of the breast:Can thermoplastic immobilization improve the reproducibility of the treatment setup and the accuracy of the delivered dose?[J].Phys Med,2015,31(1):49-53.DOI:10.1016/j.ejmp.2014.09.007.
2019, Vol. 28 
