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Catalyst系统在乳腺癌患者放疗摆位应用及影响因素分析
罗焕丽, 彭海燕, 靳富, 肖鹏, 曹绍艾, 何亚男, 董文玲, 李雪敏, 杨丁懿, 王颖
400030 重庆大学附属肿瘤医院 重庆市肿瘤研究所 重庆市肿瘤医院肿瘤放疗中心
Catalyst system in patient positioning during breast cancer radiotherapy:clinical application and influencing factors
Luo Huanli, Peng Haiyan, Jin Fu, Xiao Peng, Cao Shaoai, He Yanan, Dong Wenling, Li Xuemin, Yang Dingyi, Wang Ying
Division of Physics, Department of Radiation Oncology,Chongqing University Cancer Hospital,Chongqing Cancer Institute,Chongqing Cancer Hospital,Chongqing 400030,China
Abstract：Objective To evaluate the clinical application of Catalyst system in patient positioning during breast cancer radiotherapy, and to analyze its correlation with age and body mass index (BMI). Methods Twenty-four patients with breast cancer who were admitted to our hospital from May to August, 2016 were enrolled as subjects. For all patients, auxiliary positioning was made by the optical surface imaging system (C-Rad Catalyst) before each treatment. The kV-kV imaging was executed weekly to verify positioning. Age, BMI, and setup errors of the two systems in the anterior-posterior (AP), superior-inferior (SI), and left-right (LR) directions were recorded and analyzed by independent samples t-test and Pearson correlation analysis. Results The C-Rad Catalyst system had a significantly larger setup error in the AP direction than the kV-kV imaging (0.22±0.17 vs. 0.18±0.13 cm, P<0.05). There were no significant differences in setup errors in the SI or LR direction between the two systems (0.23±0.18 vs. 0.19±0.15 cm, P>0.05;0.28±0.28 vs. 0.20±0.15 cm, P>0.05). Age and BMI of patients had significant impacts on the C-Rad Catalyst system but the kV-kV imaging (P>0.05):there were significant differences in setup errors in the AP and SI directions between patients ≤44 years of age and those 45-59 years of age (all P<0.05);there were significant differences in setup errors in the AP and LR directions between patients ≤44 years of age and those ≥60 years of age (all P<0.05);there was a significant difference in setup error in the LR direction between patients 45-59 years of age and those ≥60 years of age (P<0.05);there was a significant difference in setup error in the SI direction between patients with BMIs of<25 and ≥25 kg/m2(P<0.05). For patients ≥60 years of age, setup error of the C-Rad Catalyst system in the SI direction was correlated with age (r=-0.496, P<0.05). For patients with BMI of<25 kg/m2, setup error of the C-Rad Catalyst system in the AP direction was correlated with BMI (r=-0.445,P<0.05). For patients with a BMI of ≥25 kg/m2, setup error of the C-Rad Catalyst system in the SI direction was correlated with BMI (r=-0.252,P<0.05). Conclusions There is significant difference in setup error in the AP direction between the C-Rad Catalyst system and the kV-kV imaging. Age and BMI have impacts on patient positioning by the C-Rad Catalyst system.
Luo Huanli,Peng Haiyan,Jin Fu et al. Catalyst system in patient positioning during breast cancer radiotherapy:clinical application and influencing factors[J]. Chinese Journal of Radiation Oncology, 2018, 27(2): 190-194.
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2018, Vol. 27 
