[an error occurred while processing this directive]
中华放射肿瘤学杂志
   2025年4月4日 星期五     首 页 |  期刊介绍  |  编 委 会  |  投稿指南  |  期刊订阅  |  广告合作  |  学术影响  |  收录情况  |  联系我们  |  English
中华放射肿瘤学杂志  2018, Vol. 27 Issue (2): 150-154    DOI: 10.3760/cma.j.issn.1004-4221.2018.02.006
·胸部肿瘤· 最新目录| 下期目录| 过刊浏览| 高级检索 [an error occurred while processing this directive]|[an error occurred while processing this directive]
基于重复增强4DCT探讨食管癌同步放化疗中心脏体积变化
王雪, 李建彬, 王金之, 张英杰, 李奉祥, 王玮, 郭延娈, 邵倩, 徐敏, 刘希军, 王越
250117 济南大学,山东省医学科学院医学与生命科学学院(王雪)
山东大学附属山东省肿瘤医院放疗科(王雪、李建彬、王金之、张英杰、李奉祥、王玮、邵倩、徐敏、刘希军),影像科(郭延娈、王越)
Application of repeated enhanced 4DCT to detect the changes of heart volume during concurrent chemoradiotherapy for esophageal cancer
Wang Xue, Li Jianbin, Wang Jinzhi, Zhang Yingjie, Li Fengxiang, Wang Wei, Guo Yanluan, Shao Qian, Xu Min, Liu Xijun, Wang Yue
School of Medicine and Life Sciences,University of Jinan-Shandong Academy of Medical Sciences (Wang X),Department of Radiation Oncology (Wang X,Li JB,Wang JZ,Zhang YJ,Li FX,Wang W,Shao Q,Xu M,Liu XJ),Department of Medical Image (GuoYL,Wang Y),Shandong Cancer Hospital Affiliated to Shandong University,Shandong Academy of Medical Sciences,Ji’nan 250117,China.
全文: PDF (0 KB)   HTML (1 KB) 
输出: BibTeX | EndNote (RIS)      背景资料
摘要 目的 基于重复4DCT模拟定位增强扫描探讨食管癌患者同步放化疗疗程中心脏体积变化。方法 食管鳞癌患者分别于放疗前及放疗10、20、30次时行4DCT及3DCT定位增强扫描。在3DCT图像及4DCT的EE和MIP图像上勾画心脏,比较疗程中心脏体积及血压、心率变化。组间比较采用配对样本t检验、单因素方差分析。结果 46例患者完成了4次3DCT及4DCT增强扫描。与初始值相比,心脏体积在放疗10次和20次时在3DCT、EE及MIP上分别下降3.27%、4.45%及4.52%和6.05%、5.64%及4.51%(P=0.000~0.027),但到放疗30次时心脏体积与初始值相近(P>0.05)。与放疗前相比,放疗结束时收缩压及舒张压下降、心率加快(P=0.000、P=0.009及 P=0.001)。结论 基于4DCT增强扫描能清晰地反映食管癌同步放化疗疗程中心脏体积变化,在放疗早期心脏体积即开始下降并持续到中后期,在放疗结束时则呈现出恢复至最初水平趋势。与此同时,疗程中血压下降,心率加快。
服务
把本文推荐给朋友
加入我的书架
加入引用管理器
E-mail Alert
RSS
作者相关文章
王雪
李建彬
王金之
张英杰
李奉祥
王玮
郭延娈
邵倩
徐敏
刘希军
王越
关键词 食管肿瘤/同步放化疗法体层摄影术 X线计算机 四维心脏体积    
AbstractObjective To detect the changes of heart volume during concurrent chemoradiotherapy for esophageal cancer based on repeated enhanced 4DCT. Methods Patients with squamous cell esophageal cancer underwent repeated enhanced 4DCT and 3DCT scans before and after 10,20 and 30 fractions of radiotherapy, respectively. The heart was contoured on 3DCT,end expiratory (EE) and maximum intensity projection (MIP) of 4DCTimages. The changes in theheart volume,blood pressure and heart rate were statistically compared at different time points. Results A total of forty-six patients completed 4 fractions of 3DCT and enhanced 4DCT scans. Compared with the initial values, the heart volume was significantly decreased by 3.27%,4.45% and 4.52% after 10 fractions of radiotherapy,and reduced by 6.05%,5.64% and 4.51% following 20 fractions of radiotherapy on 3DCT,EE and MIP,respectively (P=0.000-0.027).The heart volume after 30 fractions of radiotherapy did not significantly differ from the initial volume (P>0.05).After radiotherapy,there was a significant decrease inboth systolic and diastolic blood pressure (P=0.000 and P=0.009) and a significantincrease in the heart rate (P=0.001) compared with those measured before radiotherapy. ConclusionsEnhanced 4DCT scan can clearly reflect the changes of heart volume throughout concurrent chemoradiotherapy. The heart volume starts to shrink during the early stage of radiotherapy and continue to decrease until the middle-and late-stage, whereas it restores to the initial volume after radiotherapy. Simultaneously, blood pressure declines and heart rate is accelerated during radiotherapy.
Key words Esophageal neoplasm/concurrent chemoradiotherapy    Tomography,X-ray computed,four-dimensional    Heart volume   
收稿日期: 2017-07-31     
基金资助:国家重点研发计划项目(2016YFC0904700);山东省重点研发计划项目(2016GSF201093);山东省医药卫生科技发展计划(2015WSO160);山东省医学科学院院级科技计划项目(青年基金:2015-51)
通讯作者: 李建彬,Email:lijianbin@msn.com   
引用本文:   
王雪,李建彬,王金之等. 基于重复增强4DCT探讨食管癌同步放化疗中心脏体积变化[J]. 中华放射肿瘤学杂志, 2018, 27(2): 150-154.
Wang Xue,Li Jianbin,Wang Jinzhi et al. Application of repeated enhanced 4DCT to detect the changes of heart volume during concurrent chemoradiotherapy for esophageal cancer[J]. Chinese Journal of Radiation Oncology, 2018, 27(2): 150-154.
链接本文:  
http://journal12.magtechjournal.com/Jweb_fszlx/CN/10.3760/cma.j.issn.1004-4221.2018.02.006     或     http://journal12.magtechjournal.com/Jweb_fszlx/CN/Y2018/V27/I2/150
京公网安备11010502022167号
版权所有 © 2010《中华放射肿瘤学杂志》编辑部
地址:北京朝阳区潘学园南里17号 中国医学科学院肿瘤医院(100021)
电话:010-67700737,87788294 Email: cjron@cmaph.org
本系统由北京玛格泰克科技发展有限公司设计开发 技术支持:Support@magtech.com.cn