[1] Kim Y K, Kim B, Kim V N. Re-evaluation of the roles of DROSHA, Exportin 5, and DICER in microRNA biogenesis[J]. Proc Natl Acad Sci U S A, 2016, 113(13):E1881-E1889.DOI:10.1073/pnas.1602532113. [2] 刘尚龙.溶瘤病毒GLV-1 h151增加胰腺癌放疗敏感性的作用研究[D].北京协和医学院,2014. Liu SL.Effect of oncolytic virus GLV-1 h151 increased sensitivity of pancreatic cancer radiotherapy[D].Beijing Union Medical College, 2014. [3] 郭诗翔.miR-15a通过下调Bmi-1抑制胰腺癌细胞增殖和上皮间质转化的初步研究[D].第三军医大学,2014. Guo SX.MiR-15a inhibits the proliferation and epithelial mesenchymal transition of pancreatic cancer cells by down regulating Bmi-1[D].Third Military Medical University,2014. [4] Smither B R, Pang H Y M, Brubaker P L. Glucagon-Like Peptide-2 Requires a Full Complement of Bmi-1 for Its Proliferative Effects in the Murine Small Intestine[J]. Endocrinology, 2016, 157(7):2660-2670.DOI:10.1210/en.2016-1127. [5] 赵欣,尤胜义.miRNA在胰腺癌发生、发展及临床应用中的研究进展[J].山东医药,2015(24):101-103. Zhao X,You SY.Research progress of miRNA in the development, development and clinical application of pancreatic cancer[J].Shandong Med J,2015(24):101-103. [6] 周磊.miR-193a-3p参与调控胰腺癌细胞增殖的分子机制研究[D].中国医科大学,2014. Zhou L.Study on the molecular mechanism of miR-193a-3p involved in the regulation of pancreatic cancer cell proliferation[D].China Medical University,2014. [7] Madhavan B,Yue S,Galli U,et al. Combined evaluation of a panel of protein and miRNA serum-exosome biomarkers for pancreatic cancer diagnosis increases sensitivity and specificity[J].Int J Cancer,2015,136(11):2616-2627.DOI:10.1002/ijc.29324. [8] Shirai Y, Shiba H, Iwase R, et al. Dual inhibition of nuclear factor kappa-B and Mdm2 enhance the antitumor effect of radiation therapy for pancreatic cancer[J]. Cancer Lett, 2016, 370(2):177-184.DOI:10.1016/j.canlet.2015.10.034. [9] Wang X,Zhao J,Huang J,et al. The regulatory roles of miRNA and methylation on oncogene and tumor suppressor gene expression in pancreatic cancer cells[J].Biochem Biophys Res Commun,2012,425(1):51-57.DOI:10.1016/j.bbrc.2012.07.047. [10] Wang L, Chen C, Feng S, et al. Mitogen-activated protein kinase kinase 3 induces cell cycle arrest via p38 activation mediated Bmi-1 downregulation in hepatocellular carcinoma[J]. Mol Med Rep, 2016, 13(1):243-248.DOI:10.3892/mmr.2015.4564. [11] Klein U,Lia M,Crespo M,et al. The DLEU2/miR-15a/16-1,cluster controls b cell proliferation and its deletion leads to chronic lymphocytic leukemia[J].Cancer Cell,2010,17(1):28-40.DOI:10.1016/j.ccr.2009.11.019. [12] Musumeci M,Coppola V,Addario A,et al. Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer[J].Oncogene,2011,30(41):4231-4242.DOI:10.1038/onc.2011.140. [13] 梅自洁,苏庭世,叶俊杰,等.miRNA-15a对乳腺癌细胞放射敏感性的影响(摘要)[C] 湖北省抗癌协会青年委员会学术交流会.2012. Mei ZJ,Su TS. Ye JJ,et al. Effect of miRNA-15a on raqdiosensitivity of breast cancer cells(Abstract) [C]. Academic association of Hubei province anti cancer Association Youth Comittee.2012. [14] Guo S,Xu X,Tang Y,et al.miR-15a inhibits cell proliferation and epithelial to mesenchymal transition in pancreatic ductal adenocarcinoma by down-regulating Bmi-1 expression[J].Cancer Letters,2014,344(1):40-46.DOI:10.1016/j.canlet.2013.10.009.
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