Abstract：Objective To study the dose distribution of five clinical technologies commonly used in simulation phantom of breast cancer after radical mastectomy are observed and analyzed by using MOSFET detector. The dose validation from TPS plan is tested for clinical treatment. Methods High simulation inhomogeneous equivalent phantom of human body is used to simulate the typical patient after the operation of left breast cancer. The kay points and other points on behalf of depth to the region of interest with side of the chest wall are marked. Five radiotherapy plans (FIF-IMRT、IMRT、3DCRT、6 MeV-electron beam,9 MeV-electron beam) were designed separately on TPS based on phantom image series. After confirmed, the plans are delivered to the phantom and the dosimetrical quantities are measured. Using analysis of variance test the difference in the five methods. Results FIF-IMRT,IMRT,3DCRT,6 MeV-electron beam,9 MeV-electron beam,Five method actual measured doses respectively:Surface 74.32 cGy,69.21 cGy, 73.97 cGy,75.86 cGy,81.41 cGy (F=3.36,P<0.05);0.5 cm Depth 95.59 cGy,93.37 cGy,96.78 cGy,99.63 cGy,94.97 cGy (F=2.40,P>0.05);1.0 cm Depth 103.42 cGy,102.53 cGy,103.48 cGy,88.89 cGy,101.36 cGy (F=7.19,P<0.05);Nearly chest wall of lung 82.74 cGy,68.24 cGy,85.34 cGy,21.49 cGy,75.02 cGy (F=46.43,P<0.05). Compared to the dose value in TPS, dose delivered to Surface is lower at 8.04%(－6.57% to －11.93%),points at 0.5 cm is lower at 1.95%(2.15% to －5.90%), points at 1 cm ishigher at 0.65%(－2.87% to 3.22%),lung is lower at 3.53%(3.90% to －8.93%). ConclusionsMOSFET detector with the corresponding simulation phantom can be used to measure the actual dose in a portion of body, and to evaluate the dosimetrical characteristics of different radiotherapy techniques. MOSFET detector is suitable for real-time, in vivo measurement of radiation dose during radiotherapy in breast cancer patients, so that the physicians are able to change treatment plan in time to ensure the accuracy of target dose. DOI:10.3760/cma.j.issn.1004-4221.2015.03.026 作者单位:215006 苏州大学附属第一医院放疗科(郭建、秦颂兵、徐晓婷、王利利、詹蔚、陈龙、周菊英);上海交通大学医学院附属苏州九龙医院(蔡晓君) 通信作者:秦颂兵,Email:qin92244@163.com
. Study on radiotherapy method with simulation phantom for breast cancer after radical mastectomy[J]. Chinese Journal of Radiation Oncology, 2015, 24(3): 335-339.
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