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千伏级锥形束CT勾画心脏可行性研究
刘成新，巩贯忠，李宝生，王中堂，卢洁，刘同海，李洪升，尹勇
250117 济南大学山东省医学科学院医学与生命科学学院山东省肿瘤医院放疗科
To study the feasibility of contouring the planning organ at risk volume for heart based on kilovolt cone-beam CT images
LIU Cheng-xin, GONG Guan-zhong, LI Bao-sheng, WANG Zhong-tang, LU Jie, LIU Tong-hai, LI Hong-sheng, YIN Yong.
Department of Radiation Oncology, Shandong Cancer Hospital;School of Medicine and Life Sciences, Ji′nan University and Shandong Academy of Medical Sciences, Ji′nan 250117, China
Objective To study the feasibility of contouring heart planning organ at risk volume (PRV) on kilovolt cone-beam CT (CBCT) images, and measure the margins for the PRV of heart based on planning CT images. Methods 15 early stage non-small cell lung cancer (NSCLC) patients accepted radiotherapy in our hospital were selected. For every case, CBCT scan was achieved before every fraction to correct the setup error, and the first 10 serious CBCT images were selected in present research. After contouring the heart on CBCT images according to the same standard, compared the differences of heart between CT and CBCT, analyzed the reproducibility of contouring the heart on different serious CBCT images, measured the margins in different axial direction from heart on planning CT to CBCT. Results The heart volume of planning CT was smaller than CBCTs with statistical difference (588 cm3 vs.717 cm3,P=0.000). The volumes based on different serious CBCT images were similar for every patient (P=0.999) and the coincidence of the hearts region on the same anatomical section between the first serious CBCT and others serious could reach to 0.985±0.020 without statistical significant difference (P=0.070). The mean margins for heart from planning CT to CBCT was (10.5 ± 2.8) mm,(5.9 ± 2.8) mm,(2.2 ± 1.6) mm,(3.3 ± 2.2) mm,(6.7 ± 1.1) mm and (4.5 ± 2.5) mm in the left, right, anterior and posterior direction;respectively. Conclusions The PRV of heart contouring based on CBCT was feasible. If there were no CBCT, 11 mm in left direction, 6 mm in right direction, 3 mm in head-foot direction, 7 mm in the anterior direction, and 5 mm in posterior direction should be applied to obtain the PRV of heart.
LIU Cheng-xin,GONG Guan-zhong,LI Bao-sheng et al. To study the feasibility of contouring the planning organ at risk volume for heart based on kilovolt cone-beam CT images[J]. Chinese Journal of Radiation Oncology, 2013, 22(5): 405-407.
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2013, Vol. 22 
