Research progress on radio‐resistance mechanism of nasopharyngeal carcinoma
Yan Zhenyu1,2, Cao Xiang1,2, Hu Xinyu1,2, Ge Yizhi1, Zong Dan1, He Xia1,2
1The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research,Nanjing 210009,China; 2The Fourth School of Clinical Medicine,Nanjing Medical University,Nanjing 210000, China
Abstract：Nasopharyngeal carcinoma is one of the most common malignant head and neck tumors, and radiotherapy is the main treatment. However, radio‐resistance is a key cause of local recurrence of nasopharyngeal carcinoma. Therefore, overcoming the radio‐resistance of nasopharyngeal carcinoma and enhancing the radiosensitivity have become urgent problems in the treatment of nasopharyngeal carcinoma, which also play a key role in improving the overall survival rate of patients. In this article, recent studies on DNA, non‐coding RNA (ncRNA), protein and cell behaviors related to radio‐resistance of nasopharyngeal carcinoma were reviewed, aiming to provide valuable ideas for clinical treatment of nasopharyngeal carcinoma.
Yan Zhenyu,Cao Xiang,Hu Xinyu et al. Research progress on radio‐resistance mechanism of nasopharyngeal carcinoma[J]. Chinese Journal of Radiation Oncology, 2023, 32(3): 281-286.
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