根治性前列腺癌低分割放疗的研究进展

doi:10.3760/cma.j.cn113030-20211007-00390

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摘要放疗是局限性前列腺癌的重要治疗手段之一,既往根治性放疗为常规分割模式。近年来低分割放疗技术在根治性前列腺癌中的应用得到了快速发展,中等低分割放疗已被认为在有条件的单位可作为常规分割模式的替代方式,超低分割放疗(也称为立体定向放疗)在低中危患者中也有越来越多的证据。但高危前列腺癌的立体定向放疗的有效性及安全性还未得到充分证实。本文将对根治性前列腺癌低分割放疗的疗效、安全性及立体定向放疗相关技术的研究进展进行综述。

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	王芳
	王辛

关键词 ：前列腺肿瘤, 低分割放射疗法, 研究进展

Abstract：Radiotherapy is one of the important treatment strategies for localized prostate cancer. Conventional fractionated external beam radiotherapy is the standard dose-fraction regimen of radical radiotherapy for localized prostate cancer. In recent years, hypofractionated radiotherapy technique has been developed rapidly. The moderately hypofractionated radiotherapy has been considered as an alternative to conventional fractionated radiotherapy in conditional institutions. Increasing evidence has been obtained in the application of ultra-hypofractionated radiotherapy (also known as stereotactic body radiotherapy, SBRT) in patients with low-and intermediate-risk prostate cancer. However, the efficacy and safety of SBRT for high-risk prostate cancer have not been fully demonstrated. In this review, research progressess on the efficacy and safety of radical hypofractionated radiotherapy and the techniques of SBRT for prostate cancer were summarized.

Key words： Prostate neoplasm Hypofractionated radiotherapy Research progress

收稿日期: 2021-10-07

基金资助:国家自然科学基金面上项目(82073338);四川省科技厅项目(2021YFSY0039);四川大学华西医院临床研究孵化项目(重大项目)(2020HXFH002);四川大学华西医院学科卓越发展1·3·5工程项目(ZYJC21059)

通讯作者: 王辛,Email:wangxin213@sina.com

引用本文:

王芳,王辛. 根治性前列腺癌低分割放疗的研究进展[J]. 中华放射肿瘤学杂志, 2022, 31(1): 102-107.

Wang Fang,Wang Xin. Research progress on radical hypofractionated radiotherapy for prostate cancer[J]. Chinese Journal of Radiation Oncology, 2022, 31(1): 102-107.

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http://journal12.magtechjournal.com/Jweb_fszlx/CN/10.3760/cma.j.cn113030-20211007-00390 或 http://journal12.magtechjournal.com/Jweb_fszlx/CN/Y2022/V31/I1/102

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