Abstract: 【Purpose/significance】With the popularity of online platforms, users are more and more likely to obtain and share health information through these platforms. This study aims to explore various factors affecting the willingness to adopt health information, in order to provide a scientific basis for promoting effective health information dissemination and improving public health literacy. 【Method/process】Meta-analysis method was used to comprehensively analyze the quantitative data, identify several key influencing factors, including perceived usefulness, perceived ease of use, social impact, etc., and explore the strength and characteristics of the re⁃ lationship between these factors and the willingness to adopt online health information.【Result/conclusion】Meta-analysis identified 14 key influencing factors of willingness to adopt online health information, among which the influencing factors, such as perceived usefulness, social influence and attitude, were strongly correlated with willingness to adopt. The duration of study and platform type will partly regulate the correlation between the willingness to adopt online health information and its key influencing factors.【Innova⁃ tion/limitation】This study employs meta-analysis to extract key factors and analyze their association with adoption intentions, using research time and platform type as moderating variables. The findings provide a scientific basis for optimizing health information, de⁃ veloping services, and formulating policies. However, due to biases in the original literature and data errors, the reliability of the metaanalysis results is limited. Additionally, with insufficient data, only two moderating variables were set, making it difficult to fully con⁃ sider research differences. Future studies could broaden the search scope and further refine the variables for more in-depth analysis.