Abstract: [Purpose/significance] Based on the knowledge construction, the course system for cultivating college students' data literacy is designed to help college students master data analysis skills, develop college students' data analysis thinking, and improve college students' data literacy.[Process/Method]Based on the theory of knowledge construction, the cultivation of College Students' data lit⁃eracy is divided into three dimensions: knowledge sharing resources, knowledge dialogue and knowledge application. On the basis of cultivating students' active learning ability and data cognition ability, the "data literacy training" course with clear learning objectives and clear curriculum system structure will be built.[Results / Conclusion] The data literacy training curriculum system based on knowl⁃edge construction can promote college students to participate in learning more actively. College students can improve their learning ini⁃tiative and participation through sharing and interaction in the data literacy curriculum, and further improve their data literacy.[Limita⁃tion] This paper only designed the data literacy curriculum system, and did not conduct empirical research and evaluation on the implementation effect of the curriculum.