射波刀SBRT治疗肝门区肝癌临床疗效观察

doi:10.3760/cma.j.issn.1004-4221.2018.02.011

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Abstract Objective To evaluate the efficacy and safety of CyberKnife stereotactic body radiation therapy (SBRT) in the treatment of hepatic hilar cancer. Methods A retrospective study was performed on the clinical data of 36 patients with hepatic hilar cancer who were admitted to our hospital and treated with CyberKnife SBRT from 2009 to 2015. In the 36 patients, 37 lesions were found with tumor diameters ranging from 1.5 to 5.5 mm (median diameter 3 cm). The Synchrony respiratory tracking system was used for 21 lesions in 20 patients, while the XSight spinal tracking system was used for 16 lesions in 16 patients. Local progression was evaluated based on contrast-enhanced computed tomography and/or magnetic resonance imaging. The Kaplan-Meier method was used to calculate local control (LC) and overall survival (OS) rates, and the log-rank test was used for survival comparison and univariate prognostic analysis. Results The median follow-up time was 12.7 months. The 1-and 2-year postoperative LC rates were 90% and 76%, respectively. The 1-year OS and progression-free survival (PFS) rates were 63% and 39%, respectively. The median OS and PFS times were 15.2 and 10 months, respectively. The incidence of grade 3 adverse reactions was 11%. Conclusions The CyberKnife SBRT is a safe and effective way to treat hepatic hilar cancer.

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	Articles by authors
	Qiu Minghan
	Meng Maobin
	Zhuang Hongqing
	Wang Huanhuan
	Dong Yang
	Wang Jingsheng
	Yuan Zhiyong
	Wang Ping

Key words： Liver neopiasins/stereotactic radiotherapy Stereotactic radiotherapy, CyberKnife Treatment outcome

Received: 13 January 2017

Corresponding Authors: Yuan Zhiyong,Email:zhiyong0524@163.com

Cite this article:

Qiu Minghan,Meng Maobin,Zhuang Hongqing et al. Clinical efficacy of CyberKnife stereotactic body radiation therapy for hepatic hilar cancer[J]. Chinese Journal of Radiation Oncology, 2018, 27(2): 177-180.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2018.02.011 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2018/V27/I2/177

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