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Application of CT image correction algorithm based on image transformation in the evaluation of dose accuracy evaluation during radiotherapy for cervical cancer
Zhong Jiajian, Qiu Minmin, Xiao Zhenhua, Deng Yongjin
Department of Radiation Oncology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080,China
AbstractObjective To quantitatively evaluate dose accuracy of radiotherapy for cervical cancer. Methods A CT image correction algorithm based on image transformation was proposed. Referring to CBCT images, CT images of radiotherapy plan for cervical cancer were corrected to obtain the corrected images which could reflect the actual body position of treatment. The clinical plan was transplanted to the corrected images for dose recalculation as a test plan, and the dosimetry parameters were statistically compared to evaluate the dose accuracy. Results Both of the target coverage of contrast plans could meet the clinical requirements (>98%),and there was no significant difference in the homogeneity index (P=0.150). The conformability of the test plan was significantly worse than that of the clinical plan (P<0.05). The maximum dose of each organ at risk in the test plan was approximately 30 cGy higher than that of the clinical plan (P<0.05), V50 was slightly higher than that of the clinical plan, whereas the average dose (Dmean) did not significantly differ. Conclusion The CT image correction algorithm based on image transformation can quantitatively evaluate the dose accuracy of radiotherapy for cervical cancer, which provides reference for resolving similar problems in clinical practice.
Corresponding Authors:
Deng Yongjin,Email:dengyongjin0415@163.com
Cite this article:
Zhong Jiajian,Qiu Minmin,Xiao Zhenhua et al. Application of CT image correction algorithm based on image transformation in the evaluation of dose accuracy evaluation during radiotherapy for cervical cancer[J]. Chinese Journal of Radiation Oncology, 2019, 28(12): 914-918.
Zhong Jiajian,Qiu Minmin,Xiao Zhenhua et al. Application of CT image correction algorithm based on image transformation in the evaluation of dose accuracy evaluation during radiotherapy for cervical cancer[J]. Chinese Journal of Radiation Oncology, 2019, 28(12): 914-918.
[1]Paulino A C, Koshy M, Howell R, et al. Comparison of CT-and FDG-PET-defined gross tumor volume in intensity-modulated radiotherapy for head-and-neck cancer[J]. International Journal of Radiation OncologyBiologyPhysics, 2005, 61(5):1385-1392. DOI:10.1016/j.ijrobp.2004.08.037. [2]NesvacilN,PötterR,SturdzaA,etal. Adaptive image guided brachytherapy for cervical cancer:A combined MRI-/CT-planning technique with MRI only at first fraction[J]. Radiother Oncol,2013,107(1):75-81. DOI:10.1016/j.radonc.2012.09.005. [3]Yan D, Wong J, Vicini F, et al. 92 The use of adaptive radiation therapy to reduce setup error:A prospective clinical study[J]. International Journal of Radiation OncologyBiologyPhysics, 1996, 36(1):204-204. DOI:10.1016/S0360-3016(97)85433-8. [4]Barbara Zitová, Flusser J. Image registration methods:a survey[J]. Image and Vision Computing, 2003, 21(11):977-1000. DOI:10.1016/s0262-8856(03)00137-9. [5]Studholme C, Hill D, Hawkes D, et al. Incorporating connected region labelling into automated image registration using mutual information[C]// Workshop on Mathematical Methods in Biomedical Image Analysis. IEEE, 1996. DOI:10.1109/MMBIA.1996.534054 [6]Arun KS,Huang T S,BlosteinSD. Least-squares fitting of two 3-D point sets[J]. IEEE Trans PattAnal Mach Intell,2009,9(5):698-700. DOI:10.1109/TPAMI.1987.4767965. [7]PeriaswamyS,FaridH. Medical image registration with partial data[J]. Med Imag Anal,2006,10(3):452-464. DOI:10.1016/j.media.2005.03.006. [8]吴爱东,张绍虎,张红雁,等. 锥形束CT测量胸段食管癌调强放疗摆位误差对剂量学的影响[J]. 中华放射医学与防护杂志,2012,32(4):379-382. DOI:10.3760/cma.j.issn.0254-5098.2012.04.011WuAD,ZhangSH,ZhangHY,etal. A kV cone-beam CT based analysis of the setup errors and the corresponding impact on the dose distribution of intensity modulated radiotherapy for thoracic esophageal carcinoma[J]. Chin J Radiol Med Prot,2012,32(4):379-382. DOI:10.3760/cma.j.issn.0254-5098.2012.04.011 [9]朱小杨,王明. 放疗过程中剂量学变化研究—基于 KV-CBCT 左侧乳腺癌根治术后图像[J]. 辐射研究与辐射工艺学报,2015(3):26-30. DOI:10.11889/j.1000-3436.2015.rrj.33.030203.ZHuXY,WangM. Dosimetric study on intensity-modulated radiotherapy plans-based on kilo-voltage cone beam computed tomography images from left-sided breast cancer patients receiving modified radical mastectomy[J]. J Radiat Res Radiation,2015(3):26-30. DOI:10.11889/j.1000-3436.2015.rrj.33.030203.
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