宫颈癌放疗后生活及性生活质量分析

doi:10.3760/cma.j.issn.1004-4221.2019.08.009

Abstract
Figure/Table
References()
Related Citation (15)
Read Tracking
Download Tracking

Download: PDF (0 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS) Supporting Info

Abstract

Objective To investigate the quality of life,sexual quality of life and its influencing factors in cervical cancer patients undergoing radiotherapy. Methods Pre-menopausal patients of 87 cases were diagnosed with cervical cancer treated with radiotherapy at Peking Union Medical College Hospital from December 2013 to December 2018 were recruited in this study. The functional assessment of cancer therapy-cervix (FACT-Cx V4.0) and the female sexual function index (FSFI) were evaluated. Demographic and treatment data were collected. The influencing factors were analyzed by multiple linear regression analysis. Results The total score of quality of life was 114(100-126),19(16-21) for physiology,21(18-24) for social/family,19(17-21) for emotion,19(14-22) for function and 39(34-43) for additional attention,respectively. The end time of radiotherapy was the influencing factor of the total score (P=0.034),physiology (P=0) and function (P=0.008). Family was the influencing factor of social family dimension (P=0.010). The total score of FSFI was 8.0(5.0-20.5),1.8(1.2-3.0) for sexual desire,1.5(0-2.7) for sexual arousal,0.3(0-3.6) for vaginal lubrication,0(0-3.6) for orgasm,3.2(2-4) for satisfaction and 0(0-3.6) for sexual pain,respectively. The total score was less than 27 in 97%(84/87) of the patients and had sexual dysfunction. Age was the influencing factor of sexual arousal (P=0.005) and vaginal lubrication (P=0.039). Occupation was the influencing factor of sexual pain (P=0.004). Conclusions The quality of life of premenopausal patients with cervical cancer is affected by multiple factors. Radiotherapy-related complications should be actively treated to improve the quality of life and sexual life of patients.

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	Zhen Hongnan
	Tian Yuan
	Shen Jing
	Ma Jiabin
	Wang Wenhui
	Guan Hui
	Miao Zheng
	Zhang Yuan
	Hu Ke
	Zhang Fuquan

Key words： Cervical neoplasm/radiotherapy Quality of life Quality of sexual life

Received: 20 March 2019

Corresponding Authors: Zhang Fuquan,Email:zhangfuquan3@126.com

Cite this article:

Zhen Hongnan,Tian Yuan,Shen Jing et al. Analysis of quality of life and sexual quality of life in cervical cancer patients undergoing radiotherapy[J]. Chinese Journal of Radiation Oncology, 2019, 28(8): 597-600.

URL:

http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2019.08.009 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2019/V28/I8/597

[1] 乔友林,赵宇倩. 宫颈癌的流行病学现状和预防[J]. 中华妇幼临床医学杂志(电子版),2015,11(2):1-6. DOI:10.3877/cma.j.issn.1673-5250.2015.02.001.
Qiao YL,Zhao YQ. Epidemiological status and prevention of cervical cancer[J]. Chin J Clin Med Women Childn (elect ver),2015,11(2):1-6. DOI:10.3877/cma.j.issn.1673-5250.2015.02.001.
[2] Monk BJ,Cella D,Huang HQ,et al. Quality of life outcomes from a randomized phase Ⅲ trial of cisplatin with or without topotecan in advanced carcinoma of the cervix:a Gynecologic Oncology Group Study[J]. J Clin Oncol,2005,23(21):4626-4633.
[3] Rosen R,Brown C,Heiman J,et al.The female sexual function indes(FSF): a multidimensional self-reportinstrumentfor theassessmentof female sexual function[J]. J Sex Marital Ther,2000,26(2):191-208.
[4] 魏东红,田俊,陈桂林,等. 宫颈癌患者治疗后生存质量分析[J]. 海峡预防医学杂志,2010,16(2):20-23.
Wei DH,Tian J,Chen GL,et al. Analysis of quality of life after treatment in patients with cervical cancer[J]. J Prevent Med Straits,2010,16(2):20-23.
[5] 吴红娟,陈雪峰,潘祯,等. 宫颈癌患者放疗后生活质量现状调查及影响因素分析[J]. 中华现代护理杂志,2015,(27):3245-3249. DOI:10.3760/cma.j.issn.1674-2907.2015.27.007.
Wu HJ,Chen XF,Pan Z,et al. Investigation on the status quo of quality of life after radiotherapy in patients with cervical cancer and analysis of influencing factors[J]. Chin J Mod Nur,2015,(27):3245-3249. DOI:10.3760/cma.j.issn.1674-2907.2015.27.007.
[6] 丁钰,龚向真,胡争光,等. 子宫颈癌和子宫颈上皮内瘤变患者生命质量及相关因素分析[J]. 中国妇产科临床杂志,2012,13(2):119-121. DOI:10.3969/j.issn.1672-1861.2012.02.012.
Ding J,Gong XZ,Hu ZG,et al. Analysis of quality of life and related factors in patients with cervical cancer and cervical intraepithelial neoplasia[J]. Clin J Obstet Gynecol China,2012,13(2):119-121. DOI:10.3969/j.issn.1672-1861.2012.02.012.
[7] 鞠文翠,罗晓勇,薛聪玲.ⅠB2和ⅡA2期宫颈癌术前放疗联合手术与根治性放化疗的疗效和生活质量对比[J]. 中国妇产科临床杂志,2018,19(5):387-389. DOI:10.13390/j.issn.1672-1861.2018.05.002.
Ju WC,Luo XY,Xue CL. Comparison of the efficacy and quality of life of preoperative radiotherapy and chemotherapy for cervical cancer in ⅠB2 and ⅡA2 period[J]. Clin J Obstet Gynecol China,2018,19(5):387-389. DOI:10.13390/j.issn.1672-1861.2018.05.002.
[8] Lou WJ,Chen B,Zhu L,et al. Prevalence and factors associated with female sexual dysfunction in Beijing,China[J]. Chin Med J (Engl),2017,130(12):1389-1394. DOI:10.4103/0366-6999.207466.
[9] 赵婉君,罗晗,韩倩倩,等. 成都市女性性功能障碍的调查与相关因素的探析[J]. 中国性科学,2017,26(6):61-65. DOI:10.3969/j.issn.1672-1993.2017.06.022.
Zhao JJ,Luo H,Han JJ,et al. Investigation of female sexual dysfunction in Chengdu and analysis of related factors[J]. Chin Sex Sci,2017,26(6):61-65. DOI:10.3969/j.issn.1672-1993.2017.06.022.
[10] 左自立,辛彩霞,吴强,等. 眉山地区1003例女性性功能障碍的调查[J]. 泸州医学院学报,2017,40(2):178-181. DOI:10.3969/j.issn.2096-3351.2017.02.018.
Zuo ZL,Xin CX,Wu Q,et al. Investigation of 1003 cases of female sexual dysfunction in Meishan area[J]. J Luzhou Med Coll,2017,40(2):178-181. DOI:10.3969/j.issn.2096-3351.2017.02.018.
[11] 李致远,党云,王惠玲,等. 甘肃省女性性功能障碍患病现况调查及分析[J]. 实用妇产科杂志,2018,34(12):926-929.
Li ZY,Dang Y,Wang HL,et al. Investigation and analysis of the prevalence of female sexual dysfunction in Gansu Province[J]. J Pract Obstet gynecol,2018,34(12):926-929.
[12] Pieterse QD,Maas CP,ter Kuile MM,et al. An observational longitudinal study to evaluate miction,defecation,and sexual function after radical hysterectomy with pelvic lymphadenectomy for early-stage cervical cancer[J]. Int J Gynecol Cancer,2010,16(3):1119-1129.
[13] Frumovitz M,Sun M,Schover CC,et al. Quality of life and sexual functioning in cervical cancer survivors[J]. J Clin Oncol,2005,23(30):7428.
[14] Damast S,Alektiar K,Goldfarb S,et al. Sexual functioning among endometrial cancer patients treated with adjuvant high dose rate intra vaginal radiation therapy[J]. Int J Radiat Oncol Biol Phys,2012,84(2):e187-e193. DOI:10.1016/j.ijrobp.2012.03.030