肠道膀胱准备下不同固定方式对前列腺癌精准放疗影响

doi:10.3760/cma.j.cn113030-20210802-00282

Abstract
Figure/Table
References()
Related Citation (15)
Read Tracking
Download Tracking

Download: PDF (0 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS) Supporting Info

Abstract Objective To provide evidence for the selection of fixation devices and CTV to PTV margins (M_ptv) in precision radiotherapy for pelvic tumors by analyzing three fixation devices in precision radiotherapy for prostate cancer. Methods From April 2015 to December 2020, 133 prostate cancer patients treated with pelvic drainage area irradiation in our center were retrospectively analyzed. The patients were fixed with 1.2m vacuum bag (n=39), 1.8m vacuum bag (n=44) and personalized prone plate by our center (n=50). Each patient was asked to complete our bowel and bladder preparation process before positioning and radiotherapy. The registration of CBCT to planned CT before each treatment adopted the same registration box and algorithm. Setup errors in the SI, LR and AP directions under qualified bowel and bladder conditions were recorded. Setup errors in three directions under three fixation devices and corresponding M_ptv values were analyzed. The correlation between setup errors with age and body mass index (BMI) was analyzed. Results Analysis of 3333 setup errors data showed: in the SI and LR directions, the mean setup errors of 1.2m vacuum bag (3.26mm, 2.34mm) were greater than those of 1.8m vacuum bag (2.51mm, P<0.001; 1.90mm, P<0.001), and personalized prone plate (3.07mm, P=0.066; 2.10 mm, P=0.009). In the AP direction, the mean setup errors of 1.2m vacuum bag (supine)(2.20mm) were smaller than those of 1.8m vacuum bag (3.33mm, P<0.001) and personalized prone plate (3.61mm, P<0.001). The setup errors of 1.8m vacuum bag in all directions were smaller than those of personalized prone plate (P≤0.028). According to Van Herk's expansion formula, the M_ptv of 1.2m vacuum bag in three directions was approximately 4 mm. The M_ptv of 1.8m vacuum bag and personalized prone plate in the SI and LR directions was approximately 3 mm, and more than 5 mm in the AP direction. The setup errors were not correlated with age or BMI. Conclusions From the setup errors results of three devices, 1.8m vacuum bag is the best, followed by personalized prone plate. And supine position is better than prone position in the AP direction.

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	Huang Sijuan
	Zhong Ziyue
	Tang Hao
	Liu Yang
	He Mengxue
	Guo Xuan
	He Liru
	Lin Zhiyue
	Yao Wenyan
	Xu Senkui
	Yang Xin

Key words： Prostatic Neoplasms Fixation Setup error Bowel and bladder preparation protocol

Received: 02 August 2021

Fund:Sun Yat‐sen University Cancer Center Youth Excellence Program(QNYCPY32); Innovation and Entrepreneurship Training Program for College Student Innovation and Entrepreneurship(S202113902030、202113902116)

Corresponding Authors: Yang Xin, Email:yangxin@sysucc.org.cn

Cite this article:

Huang Sijuan,Zhong Ziyue,Tang Hao et al. Analysis of different fixation devices in precision radiotherapy for prostate cancer under bowel and bladder preparation protocol[J]. Chinese Journal of Radiation Oncology, 2022, 31(8): 716-721.

URL:

http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.cn113030-20210802-00282 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2022/V31/I8/716

[1] 中国医师协会放射肿瘤治疗医师分会,中华医学会放射肿瘤治疗学分会,中国抗癌协会肿瘤放射治疗专业委员会.中国前列腺癌放射治疗指南(2020年版)[J]. 中华肿瘤防治杂志,2021,28(5):323‐337.DOI: 10.16073/j.cnki.cjcpt.2021.05.01
Radiation Therapy Branch of Chinese Medical Association, Radiation therapy Branch of Chinese Medical Association, Radiation Therapy Professional Committee of Chinese Anti‐Cancer Association.Guidelines for radiotherapy of prostate cancer in China (2020 Edition)[J]. Chin J Cancer Prev Treat.2021,28(5):323‐337.DOI: 10.16073/j.cnki.cjcpt.2021.05.01
[2] 中国医促会泌尿健康促进分会,中国研究型医院学会泌尿外科学专业委员会.前列腺癌放射治疗安全共识[J]. 现代泌尿外科杂志,2019,24(5):336‐346.DOI: 10.3969/j.issn.1009‐8291.2019.05.003
Urological Health Promotion Branch of China Medical Promotion Association, Urological Surgery Professional Committee of Chinese Research Hospital Society.Safety consensus of radiotherapy for prostate cancer[J]. J Modern Urol, 2019,24(5):336‐346.DOI: 10.3969/j.issn.1009‐8291.2019.05.003
[3] Ghadjar P, Thalmann GN.Comparative analysis of prostate‐specific antigen free survival outcomes for patients with low, intermediate and high risk prostate cancer treatment by radical therapy.Results from the Prostate Cancer Results Study Group[J]. BJU Int, 2012,110(10):E431‐432; author reply E432.DOI: 10.1111/j.1464‐410X.2012.11624.x.
[4] Olsson CE, Jackson A, Deasy JO, et al.A systematic post‐QUANTEC review of tolerance doses for late toxicity after prostate cancer radiation therapy[J]. Int J Radiat Oncol Biol Phys, 2018,102(5):1514‐1532.DOI: 10.1016/j.ijrobp.2018.08.015.
[5] Krol R, McColl GM, Hopman W, et al.Anal and rectal function after intensity‐modulated prostate radiotherapy with endorectal balloon[J]. Radiother Oncol, 2018,128(2):364‐368.DOI: 10.1016/j.radonc.2018.03.032.
[6] Zhang B, Lee SW, Chen S, et al.Action levels on dose and anatomic variation for adaptive radiation therapy using daily offline plan evaluation: preliminary results[J]. Pract Radiat Oncol, 2019,9(1):49‐54.DOI: 10.1016/j.prro.2018.08.006.
[7] Posiewnik M, Piotrowski T.A review of cone‐beam CT applications for adaptive radiotherapy of prostate cancer[J]. Phys Med, 2019,59:13‐21.DOI: 10.1016/j.ejmp.2019.02.014.
[8] White P, Yee CK, Shan LC, et al.A comparison of two systems of patient immobilization for prostate radiotherapy[J]. Radiat Oncol, 2014,9:29.DOI: 10.1186/1748‐717X‐9‐29.
[9] 陈亚雄,王一鸣,孔繁忠,等.CBCT用于50例盆腔恶性肿瘤放疗摆位误差的分析[J]. 中华肿瘤防治杂志, 2019,26(18):1382‐1386.DOI: 10.16073/j.cnki.cjcpt.2019.18.12.
Cheng YX, Wang YM, Kong FZ, et al.CBCT was used to analyze the positioning error of radiotherapy for 50 cases of pelvic malignant tumor[J]. Chin J Cancer Prev Treat, 2019,26(18):1382‐1386.DOI: 10.16073/j.cnki.cjcpt.2019.18.12.
[10] 彭庆国,尹勇,余宁莎,等.三种体位固定技术在盆腔肿瘤放疗中的应用比较[J]. 中华肿瘤防治杂志,2015,22(12):974‐977,983.
Peng QG, Yin Y, Yu NS, et al.Compare the application of the three positioning methods in tumor of pelvis radiotherapy[J]. Chin J Cancer Prev Treat, 2015,22(12):974‐977,983.
[11] Inui S, Ueda Y, Ohira S, et al.Comparison of interfractional setup reproducibility between two types of patient immobilization devices in image‐guided radiation therapy for prostate cancer[J]. J Med Phys, 2018,43(4):230‐235.DOI: 10.4103/jmp.JMP_20_18.
[12] Udayashankar AH, Noorjahan S, Srikantia N, et al.Immobilization versus no immobilization for pelvic external beam radiotherapy[J]. Rep Pract Oncol Radiother, 2018,23(4):233‐241.DOI: 10.1016/j.rpor.2018.04.007.
[13] van Herk M.Errors and margins in radiotherapy[J]. Semin Radiat Oncol, 2004,14(1):52‐64.DOI: 10.1053/j.semradonc.2003.10.003.
[14] Ricotti R, Pella A, Tagaste B, et al.Long‐time clinical experience in patient setup for several particle therapy clinical indications: management of patient positioning and evaluation of setup reproducibility and stability[J]. Br J Radiol, 2020,93(1107):20190595.DOI: 10.1259/bjr.20190595.
[15] Mulla Z, Hashem RM, Almohamad A, et al.A comparison between two different immobilization devices for radiation therapy treatment of pelvic cancer using VMAT[J]. J Med Imaging Radiat Sci, 2021,52(2):238‐247.DOI: 10.1016/j.jmir.2021.02.008.
[16] Hubie C, Shaw M, Bydder S, et al.A randomised comparison of three different immobilisation devices for thoracic and abdominal cancers[J]. J Med Radiat Sci, 2017,64(2):90‐96.DOI: 10.1002/jmrs.202.
[17] 袁响林,熊慧华,于世英,等.俯卧位腹部托板用于直肠癌术后辅助性放疗的剂量学研究[J]. 中华放射肿瘤学杂志, 2007,16(5):400‐402.DOI: 10.3760/j.issn: 1004‐4221.2007.05.021
Yuan XL, Xiong HH, Yu SHY, etal.Dosimetry study of abdominal support plate in prone position for postoperative adjuvant radiotherapy of rectal cancer[J]. Chin J Radiat Oncol, 2007,16(5):400‐402.DOI: 10.3760/j.issn: 1004‐4221.2007.05.021
[18] Sawayanagi S, Yamashita H, Ogita M, et al.Volumetric and dosimetric comparison of organs at risk between the prone and supine positions in postoperative radiotherapy for prostate cancer[J]. Radiat Oncol, 2018,13(1):70.DOI: 10.1186/s13014‐018‐1023‐0.
[19] Hoisak J, Pawlicki T.The role of optical surface imaging systems in radiation therapy[J]. Semin Radiat Oncol, 2018,28(3):185‐193.DOI: 10.1016/j.semradonc.2018.02.003.
[20] Leong B, Padilla L.Impact of use of optical surface imaging on initial patient setup for stereotactic body radiotherapy treatments[J]. J Appl Clin Med Phys, 2019,20(12):149‐158.DOI: 10.1002/acm2.12779.
[21] Yartsev S, Bauman G.Target margins in radiotherapy of prostate cancer[J]. Br J Radiol, 2016,89(1067): 20160312.DOI: 10.1259/bjr.20160312.
[22] de Crevoisier R, Pommier P, Latorzeff I, et al.Prostate cancer external beam radiotherapy[J]. Cancer Radiother, 2016,20 Suppl: S200‐209.DOI: 10.1016/j.canrad.2016.07.037.
[23] Marnouche EA, Hadadi K, Abdelhak M, et al.Evaluation of margins in pelvic lymph nodes and prostate radiotherapy and the impact of bladder and rectum on prostate position[J]. Cancer Radiother, 2021,25(2):161‐168.DOI: 10.1016/j.canrad.2020.06.033.
[24] 李雅宁,林承光,杨鑫.体质量指数对宫颈癌调强放疗摆位误差影响[J]. 中华放射肿瘤学杂志, 2021,30(2):186‐190.DOI: 10.3760/cma.j.cn113030‐20191014‐00420.
Li YN, Lin CG, Yang X.Effect of body mass index on setup errors in intensity‐modulated radiotherapy for cervical cancer[J]. Chin J Radiat Oncol, 2021,30(2):186‐190.DOI: 10.3760/cma.j.cn113030‐20191014‐00420.
[25] Pan JH, Yu DD, Song QB, et al.Comparison of geometrical uncertainties in the radiotherapy for various treatment sites with two different immobilization marking methods[J]. J Xray Sci Technol, 2019,27(4):703‐714.DOI: 10.3233/XST‐180467.
[26] 唐涛,石翔翔,庞皓文,等.妇科肿瘤调强放疗摆位方法和误差分析及与体重指数的关系[J]. 泸州医学院学报, 2015,38(5):498‐501.DOI: 10.3969/j.issn.1000‐2669.2015.05.018.
Tang T, Shi XX, Pang HW, et al.Positioning method and relationship with setup errors and BMI in the patients treated with intensity‐modulated radiation therapy for gynecological malignancies[J]. J Luzhou Med Colleg, 2015,38(5):498‐501.DOI: 10.3969/j.issn.1000‐2669.2015.05.018.
[27] Brown A, Tan A, Cooper S, et al.Obesity does not influence prostate intrafractional motion[J]. J Med Radiat Sci, 2018,65(1):31‐38.DOI: 10.1002/jmrs.255.