放疗中皮肤弹性与摆位误差随年龄变化的相关性研究

doi:10.3760/cma.j.issn.1004-4221.2020.01.011

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Abstract Objective To investigate the correlation between skin elasticity and setup error in optical surface image-guided radiotherapy. Methods The skin elasticity (R7) data of the head, chest and abdomen were extracted and analyzed its correlation with age by systematic literature review. Fifty-four patients diagnosed with nasopharyngeal carcinoma, breast cancer and cervical cancer were recruited in this study. Firstly,the patients were positioned based on the room laser and markers. Subsequently, the patient position was verified by the Varian On-Board Imager, and then C-Rad Catalyst was adopted to obtain surface images in two states (mask or non-mask) as reference images. In the subsequent fraction treatment,after initial positioning,the local calibration was performed by Catalyst,and setup errors in three directions were recorded. Meanwhile,the patient setup was verified by CBCT twice a week. The Pearson correlation analysis was performed to analyze the correlation between setup error and age. Results The skin elasticity was negatively correlated with aging (P<0.01). The correlation coefficient between random error and age in head-and-neck cancer were 0.645,0.624 and 0.866 in the AP,SI and LR directions (all P<0.05) for male patients without mask,respectively. The system error was significantly correlated with age in the LR direction (P<0.05) for male patients,and in the AP direction (P<0.05) for female patients with head-and-neck cancer without mask. The setup error had a significant correlation with skin elasticity in male patients with head-and-neck cancer,and the sequence of absolute value of correlation coefficient was LR>SI>AP. Conclusion In optical surface-guided radiotherapy of head and neck cancer,skin elasticity may be a significant index for assessing the setup errors in male patients.

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	Articles by authors
	He Yang
	Lei Jinyan
	Peng Haiyan
	Luo Huanli
	Mao Kaijin
	Wang Dengyan
	Peng Lifeng
	Zhu Yiyu
	Min Qinghong
	Wang Xuechun
	Tang Huan
	Xiao Peng
	Xiao Qiang
	Wang Ying
	Jin Fu

Key words： Skin elasticity Surface image-guided radiotherapy Set-up error

Received: 31 May 2018

Corresponding Authors: Jin Fu,Email:jfazj@126.com

Cite this article:

He Yang,Lei Jinyan,Peng Haiyan et al. The effect of age on skin elasticity and setup error in optical surface image-guided radiotherapy[J]. Chinese Journal of Radiation Oncology, 2020, 29(1): 47-51.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2020.01.011 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2020/V29/I1/47

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