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Progress in adjuvant therapy decision-making after endoscopic resection of early esophageal cancer
Feng Lingling1, Men Yu2, Hui Zhouguang2
1Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital,Chinese Academy of Medical Sciences,Peking Union Medical College,Shenzhen 518116,China; 2Department of VIP Medical Servicess, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021,China
Abstract Both endoscopic resection and surgery are the common treatment modes for early esophageal cancer. Compared with radical surgery,endoscopic resection has the advantages of less trauma,quicker recovery,lower cost,less complications,the preservation of the normal anatomy,the physiological function of the esophagus,and higher postoperative quality of life. For patients with a high risk of lymph node metastasis, endoscopic resection alone can lead to inadequate treatment,which need adjuvant therapies. Currently, the common adjuvant therapies consist of adjuvant radiochemotherapy and adjuvant radiochemotherapy combined with surgery. How to combine endoscopic resection with adjuvant therapy to bring maximal benefits to patients has become the hot topic in the field of clinical researches. In this article, the current research status,progress and challenges in the combination of endoscopic resection and adjuvant therapy for the treatment of high-risk patients were reviewed.
Fund:National Key Research and Development Program (2017YFC1311000);National Natural Science Foundation of China (81372418);Medical and Health Science and Technology Innovation Project,Chinese Academy of Medical Sciences (Major Collaborative Innovation Project 2016-I2M-1-011)
Feng Lingling,Men Yu,Hui Zhouguang. Progress in adjuvant therapy decision-making after endoscopic resection of early esophageal cancer[J]. Chinese Journal of Radiation Oncology, 2019, 28(11): 867-871.
Feng Lingling,Men Yu,Hui Zhouguang. Progress in adjuvant therapy decision-making after endoscopic resection of early esophageal cancer[J]. Chinese Journal of Radiation Oncology, 2019, 28(11): 867-871.
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