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Dosimetric analysis of CT-guided salvage interstitial brachytherapy for recurrent cervical cancer
Liu Zhongshan, Guo Jie, Zhao Yangzhi, Lin Xia, Zhang Zhiliang, Wang Hongyong, Li Yunfeng, Ren Xiaojun, Zhang Bingya, Wang Tiejun
Department of Radiation Oncology, the Second Affiliated Hospital of Jilin University, Changchun 130041,China (Liu ZS, Guo J, Lin X, Zhang ZL, Wang HY, Li YF, Ren XJ, Zhang BY, Wang TJ); Cancer Center, the First Affiliated Hospital of Jilin University, Changchun 130021, China (Zhao YZ)
AbstractObjective To analyze the dosimetric advantages of CT-guided interstitial brachytherapy for recurrent cervical cancer. Methods A total of 16 patients with recurrent cervical cancer after radical surgery and adjuvant external beam radiotherapy received interstitial brachytherapy with CT-guided implantation of metal needles. The high-risk clinical target volume (HR-CTV) was given 36 Gy in 6 fractions. D90 for HR-CTV in the brachytherapy and the cumulative D2 cm3 values for the bladder, rectum, and sigmoid colon in the previous external beam radiotherapy and the brachytherapy were analyzed. Results The mean D90 value for HR-CTV was 52.5±3.3 Gy. The cumulative D2 cm3 values for the bladder, rectum, and sigmoid colon were 85.6±5.8 Gy, 71.6±6.4 Gy, and 69.6±5.9 Gy, respectively. The mean number of metal needles was 6.1±1.5 in each brachytherapy. The actual 1-year overall survival and local control were 81% and 69%, respectively. Conclusions CT-guided interstitial brachytherapy for recurrent cervical cancer shows good dose-volume histogram parameters and few complications, so it may be clinically feasible. However, its long-term clinical efficacy needs further observation.
Corresponding Authors:
Wang Tiejun, Email wangtiejunjlu@163.com
Cite this article:
Liu Zhongshan,Guo Jie,Zhao Yangzhi et al. Dosimetric analysis of CT-guided salvage interstitial brachytherapy for recurrent cervical cancer[J]. Chinese Journal of Radiation Oncology, 2018, 27(1): 74-78.
Liu Zhongshan,Guo Jie,Zhao Yangzhi et al. Dosimetric analysis of CT-guided salvage interstitial brachytherapy for recurrent cervical cancer[J]. Chinese Journal of Radiation Oncology, 2018, 27(1): 74-78.
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2018, Vol. 27 
