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The past,present,and future of radiotherapy for stage IV non-small cell lung cancer
Lu Bing, Su Shengfa, He Zhixu
Department of Thoracic Oncology,Affiliated Hospital of Guizhou Medical University,Guizhou Cancer Hospital,Guiyang 550004,China (Lu B,Su SF); Guizhou Medical University,Guizhou Cancer Hospital,Guiyang 550025,China (He ZX);
Abstract The efficacy of palliative care was definitive with two-dimensional radiotherapy for stage IV non-small cell lung cancer (NSCLC).However,theimpact of radiotherapy on survival was not well indicated,and some study resultsindicating prolonged survival were not accepted. Along with the advancesin three-dimensional radiotherapy (3DRT),wide application of comprehensive treatment,and the understanding of the association between different metastatic status and survival,prospective and retrospective studies have demonstrated that chemotherapy combined with 3DRT for primary tumor is more effective than chemoradiotherapy alone in improving symptoms and prolonging survival,especially for oligometastases of stage IV NSCLC.The dose to primary tumor is closely related to survival,and high-dose radiotherapy may be more likely to prolong survival. Further studies,however,areneeded to take into accountproblems such as thedose,timing,and technical selection of radiotherapy.
Fund:Major Special Project of Basic Research for Application of Guizhou Province (Qian-J-Zhong[2015] 2003);Major Research Project of The Innovation Group of The Education Department of Guizhou Province (Qian-KY[2016] 032)
Cite this article:
Lu Bing,Su Shengfa,He Zhixu. The past,present,and future of radiotherapy for stage IV non-small cell lung cancer[J]. Chinese Journal of Radiation Oncology, 2018, 27(1): 29-34.
Lu Bing,Su Shengfa,He Zhixu. The past,present,and future of radiotherapy for stage IV non-small cell lung cancer[J]. Chinese Journal of Radiation Oncology, 2018, 27(1): 29-34.
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2018, Vol. 27 
