基于肠道菌群的肠放射损伤生物标记物研究进展

doi:10.3760/cma.j.issn.1004-4221.2020.03.018

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Abstract Recently,the relationship between intestinal flora and its metabolites and tumorigenesis,inflammatory bowel diseasesas well as radiation-induced intestinal injury has captivated widespread attention from researchers. Accumulated evidence derived from nuclear accident investigation,animal model experiment and clinical research has proven the role of intestinal flora and its metabolites as the biomarkers to evaluate the radiation dose and severity of radiation-induced intestinal injury. This article reviews the relationship between intestinal flora and its metabolites and radiation-induced intestinal injury, aiming to provide theoretical reference for assessing the risk of radiation-induced intestinal injury.

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	Articles by authors
	Zhang Junjun
	Cai Shang
	Yang Yongqiang
	Li Junyan
	Tian Ye

Key words： Intestinal flora Metabolite Radiation-induced injury Biomarker

Received: 03 November 2018

Fund:Jiangsu Medical Innovation Team (CXDT-37);Suzhou Science and Technology Development Program (SZS201509);Pre-research Program of the SecondAffiliated Hospital of Soochow University (SDFEYBS1701)

Corresponding Authors: Tian Ye,Email:dryetian@126.com

Cite this article:

Zhang Junjun,Cai Shang,Yang Yongqiang et al. Research progress on biomarkers for radiation-induced intestinal injury based on intestinal flora[J]. Chinese Journal of Radiation Oncology, 2020, 29(3): 237-240.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2020.03.018 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2020/V29/I3/237

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