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Research progress on treatment of esophageal perforation in esophageal carcinoma
Qi Xinrui,Liang Jun
Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021,China
Abstract Esophageal cancer is one of the common tumors in China. Esophageal perforation is a common complication of esophageal carcinoma. Currently,there is no consensus on the treatment of esophageal perforation of esophageal carcinoma at home and abroad. Twenty-seven articles were selected from PubMed,CNKI and Wanfang database between 1997 to December 2017. The mechanism of esophageal perforation and clinical characteristics in these 27 articles were analyzed. Surgery can improve the survival rate, but the risk of perioperative complications may be increased. Concurrent chemoradiotherapy with nutritional support can significantly improve the survival rate.
Qi Xinrui,Liang Jun. Research progress on treatment of esophageal perforation in esophageal carcinoma[J]. Chinese Journal of Radiation Oncology, 2019, 28(9): 713-716.
Qi Xinrui,Liang Jun. Research progress on treatment of esophageal perforation in esophageal carcinoma[J]. Chinese Journal of Radiation Oncology, 2019, 28(9): 713-716.
[1] 左婷婷,郑荣寿,曾红梅,等. 中国食管癌发病状况与趋势分析[J]. 中华肿瘤杂志,2016,38(9):703-708. DOI:10.3760/cma.j.issn.0253-3766.2016.09.013. Zuo TT,Zheng RS,Zeng HM,et al. Analysis of the pathogenesis and trend of esophageal cancer in China[J]. Chin J Oncol,2016,38(9):703-708. DOI:10.3760/cma.j.issn.0253-3766.2016.09.013. [2] 陈尔成,刘孟忠,胡永红,等. 不能手术切除行同期放化疗的食管癌患者预后的多因素分析[J]. 癌症,2005,24(6):731-734. DOI:10.3321/j.issn:1000-467X.2005.06.021. Chen EC,Liu M,Hu YH,et al. Multi-factor analysis of prognosis of esophageal cancer patients undergoing simultaneous radiotherapy and chemotherapy[J]. Cancer,2005,24(6):731-734. DOI:10.3321/j.issn:1000-467X.2005.06.021. [3] 肖泽芬. 食管癌[A]//殷蔚伯,谷铣之等. 肿瘤放射治疗学[M].5版. 北京:中国协和医科大学出版社,2018:833. Xiao ZF. Esophageal carcinoma[A]//Yin WB,Gu XZ,et al. Radiation oncology[M].5th ed. Beijing:Peking union medical college press,2018:833. [4] Tu L,Lan S,Yong X,et al. Paclitaxel and cisplatin combined with intensity-modulated radiotherapy for upper esophageal carcinoma[J]. Radiat Oncol,2013,8(1):75(1-6). DOI:10.1186/1748-717X-8-75. [5] Wang Q,Li T,Lang J,et al. A retrospective study of californium-252 neutron brachytherapy combined with EBRT versus 3D-CRT in the treatment of esophageal squamous cell cancer[J]. Radiat Oncol,2015,10(1):212(1-8). DOI:10.1186/s13014-015-0520-7. [6] Biancari F,D'Andrea V,Paone R,et al. Current treatment and outcome of esophageal perforations in adults:systematic review and meta-analysis of 75 studies[J]. World J Surg,2013,37(5):1051-1059. DOI:10.1007/s00268-013-1951-7. [7] 肖泽芬,杨宗贻,吕宁,等.放疗治疗食管癌穿孔预后因素的分析[J].中华放射肿瘤学杂志,1997,6(3):218-220. DOI:10.3760/j.issn:1004-4221.1997.04.004. Xiao ZF,Yang ZY,Lyu N,et al. Analysis of prognostic factors of esophageal carcinoma perforationJ]. Chin J Radiat Oncol,1997,6(3):218-220. DOI:10.3760/j.issn:1004-4221.1997.04.004. [8] 孙联军.18例食管癌穿孔的诊治探讨[J]. 中国医药导报,2008,5(2):240-240. DOI:10.3969/j.issn.1673-7210.2008.24.167. Sun LJ. Diagnosis and treatment of 18 cases of esophageal carcinoma perforation[J]. Chin Med Guide,2008,5(2):240-240. DOI:10.3969/j.issn.1673-7210.2008.24.167. [9] 顾恺时. 胸心外科手术学[M].上海:科学技术出版社,2003:932-934.Gu KS. Thoracic surgery[M]. Shanghai:Science and technology press,2003:932-934. [10] 杨军,王亚军. 食管癌放疗后并发食管穿孔的临床治疗研究[J]. 中国继续医学教育,2016,8(1):86-87. DOI:10.3969/j.issn.1674-9308.2016.29.050. Yang J,Wang YJ. Clinical treatment of esophageal perforation after radiotherapy for esophageal carcinoma[J]. Cont Med Educat China,2016,8(1):86-87. DOI:10.3969/j.issn.1674-9308.2016.29.050. [11] Han X,Zhao YS,Fang Y,et al. Placement of transnasal drainage catheter and covered esophageal stent for the treatment of perforated esophageal carcinoma with mediastinal abscess[J]. Journal of Surgical Oncology,2016,114(6):725-730. DOI:10.1002/jso.24384. [12] 于金明,殷蔚伯,李宝生. 肿瘤精确放疗学(上卷)[M]. 济南:山东科学技术出版社,2003. Yu JM,Ying WB,Li BS. Tumor precision radiotherapy (up vol)[M]. Jinan:Shandong science and technology press,2003. [13] Chen HY,Ma XM,Ye M,et al. Esophageal perforation during or after conformal radiotherapy for esophageal carcinoma[J]. J Radiat Res,2014,55(5):940-947. DOI:10.1093/jrr/rru031. [14] Zhou ZG,Zhen CJ,Bai WW,et al. Salvage radiotherapy in patients with local recurrent esophageal cancer after radical radiochemotherapy[J]. Radiat Oncol,2015,10(1):1-7. DOI:10.1186/s13014-015-0358-z. [15] 樊青霞,王瑞林. 食管癌[M]. 北京:科学技术文献出版社,2009. Fan QX,Wang RL. Esophageal cancer[M]. Beijing:Science and technology literature press,2009. [16] 段德溥,邹济华,才志刚,等.36例食管癌穿孔的手术治疗[J]. 中国肿瘤临床,2006,33(10):571-573. DOI:10.3969/j.issn.1000-8179.2006.10.010. Duan DP,Zou JH,Cai ZG,et al. Surgical treatment of 36 cases of esophageal carcinoma perforation[J]. Chin J Clin Oncol,2006,33(10):571-573. DOI:10.3969/j.issn.1000-8179.2006.10.010. [17] Aquino JLBD,Camargo JGTD,Cecchino GN,et al. Evaluation of urgent esophagectomy in esophagealperforation[J]. Arq Bras Cir Dig,2014,27(4):247-250. DOI:10.1590/S0102-67202014000400005. [18] 邹济华,梁翔,段德溥,等. 食管癌穿孔外科治疗的临床分析[J]. 癌症,2008,27(2):174-177. DOI:10.3321/j.issn:1000-467X.2008.02.012. Shi JH,Liang X,Duan DP,et al. Clinical analysis of surgical treatment of esophageal carcinoma perforation[J]. Chin J Cancer,2008,27(2):174-177. DOI:10.3321/j.issn:1000-467X.2008.02.012. [19] Chang J,Sharma G,Boules M,et al. Endoscopic stents in the management of anastomotic complications after foregut surgery:new applications and techniques[J]. Surg Obes Rel Dis,2016,12(2016):1373-1381. DOI:10.1016/j.soard.2016.02.041. [20] 李学兆. 支架植入食管癌患者23例临床获益性分析[J]. 中国实用医药,2015,10(2):101-102. DOI:10.14163/j.cnki.11-5547/r.2015.10.066. Li XZ. Clinical benefit analysis of 23 patients with stent implantation in esophageal cancer[J]. China Pract Med,2015,10(2):101-102. DOI:10.14163/j.cnki.11-5547/r.2015.10.066. [21] Abe T,Tangoku AH,Takeda S,et al. Esophageal perforation and mediastinal abscess following placement of a covered self-expanding metallic stent and radiation therapy in a cancer patient[J]. Surg Endoscopy,1999,13(10):1044-1046. DOI:10.1007/s004649901166. [22] Zhu HD,Guo JH,Mao AW,et al. Conventional stents versus stents loaded with 125 iodine seeds for the treatment of unresectable oesophageal cancer:a multicentre,randomised phase 3 trial[J]. Lancet Oncol,2014,15(6):612-619. DOI:http://dx.doi.org/10.1016/S1470-2045(14)70131-7. [23] 张涛,王波. 碘-125放射性粒子覆膜支架置入对晚期食管癌的有效性与安全性分析[J]. 实用癌症杂志,2018,33(2):283-286. DOI:10.3969/j.issn.1001-5930.2018.02.033. Zhang T,Wang B. Analysis on the efficacy and safety of iodine-125 radioactive particle coated stent implantation in advanced esophageal cancer[J]. J Pract Cancer,2018,33(2):283-286. DOI:10.3969/j.issn.1001-5930.2018.02.033. [24] Ma L,Luo GY,Ren YF,et al. Concurrent chemoradiotherapy combined with enteral nutrition support:a radical treatment strategy for esophageal squamous cell carcinoma patients with malignant fistulae[J]. Cancer,2017,36(1):26-33. DOI:10.1186/s40880-016-0171-6. [25] 吴莹嘉,郭素萍,黄滨莲,等.82例食管癌同期放化疗致食管穿孔患者的护理[J]. 护理学报,2012,19(16):32-33. DOI:10.3969/j.issn.1008-9969.2012.16.010. Wu YY,Guo SP,Huang BL,et al. Nursing care of 82 patients with esophageal perforation caused by simultaneous radiotherapy and chemotherapy in esophageal carcinoma[J]. J Nursing,2012,19(16):32-33. DOI:10.3969/j.issn.1008-9969.2012.16.010. [26] Ham YH,Kim GH. Plastic and biodegradable stents for complex and refractory benign esophageal strictures[J]. Clinl Endoscopy,2014,47(4):295-300. DOI:10.5946/ce.2014.47.4.295. [27] 曾海燕,袁双虎,孟雪,等. 食管癌放疗穿孔防治研究进展[J]. 中华肿瘤防治杂志,2017,24(7):501-506. DOI:10.16073/j.cnki.cjcpt.2017.07.014. Zeng HY,Yuan SH,Meng X,et al. Research progress in prevention and treatment of radiotherapy for esophageal carcinoma[J]. Chin J Oncol,2017,24(7):501-506. DOI:.10.16073/j.cnki.cjcpt.2017.07.014.
2019, Vol. 28 
