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Introduction of image-guided stereotactic radiotherapy systems for small animals
Qing Gan, Wang Jiazhou, Hu Weigang, Zhang Zhen
Medical School of Fudan University, Shanghai 200032,China (Qing G) Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032,China (Zhang Z, Hu WG, Wang JZ)
Abstract The theory and application of small animal radiotherapy models is critical for the research and development of radiobiology and clinical radiotherapy. Considering universality and cost effects, mouse models are widely used to explore the radiobiological mechanisms of cancerous and normal tissues. In recent years, there has been tremendous progress in image-guided stereotactic radiotherapy equipment for small animals, which could simulate the human radiotherapy process. This article introduces stereotactic radiotherapy systems for small animals guided by different imaging modalities, such as cone-beam computed tomography and magnetic resonance imaging, and then reviews small animal fluorescence imaging technology and summarizes the application of different bioluminescence and fluorescence imaging equipment in small animal imaging systems. Finally, we put forward the prospect of optimization direction of radiotherapy equipment for small animals in future.
Qing Gan,Wang Jiazhou,Hu Weigang et al. Introduction of image-guided stereotactic radiotherapy systems for small animals[J]. Chinese Journal of Radiation Oncology, 2018, 27(2): 222-225.
Qing Gan,Wang Jiazhou,Hu Weigang et al. Introduction of image-guided stereotactic radiotherapy systems for small animals[J]. Chinese Journal of Radiation Oncology, 2018, 27(2): 222-225.
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2018, Vol. 27 
