金纳米颗粒在肿瘤放射增敏中的相关研究进展

doi:10.3760/cma.j.issn.1004-4221.2017.07.025

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Abstract Nanotechnology has been extensively applied in the diagnosis and treatment of cancer, and is currently a major focus of research worldwide. Among the various nanomaterials, gold nanoparticles (GNPs) are of particular interest to many researchers due to their superior properties of low cytotoxicity, good biocompatibility, and preferential accumulation in tumors (the “enhanced permeability and retention” effect), which in turn gives GNPs a potential application in cancer diagnostics, imaging, photothermal therapy, and radiotherapy. Many published studies have shown that GNPs can be used as a new ideal radiosensitizer, and therefore understanding the radiosensitizing effects of GNPs both in vitro and in vivo will be of great significance in the clinical translation of nanomedicine.

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	Articles by authors
	Zhao Ning
	Fu Shen

Key words： Gold nanoparticles Physical properties Radiosensitization Clinical application

Received: 09 November 2016

Fund:National Natural Science Foundation of China (81272506);Foundation of Shanghai Municipal Science and Technology Commission (12JCl407400);The Key Project of Biomedical Engineering Cross Research Foundation of Shanghai Jiao Tong University (YG2012ZD02)

Corresponding Authors: Fu Shen,Email:shen_fu@hotmail.com

Cite this article:

Zhao Ning,Fu Shen. Research advances in gold nanoparticle-mediated tumor radiosensitization[J]. Chinese Journal of Radiation Oncology, 2017, 26(7): 838-841.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2017.07.025 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2017/V26/I7/838

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