CT引导辅助3D打印个体化非共面模板指导<sup>125</sup>I粒子治疗盆腔复发肿瘤剂量学研究

doi:10.3760/cma.j.issn.1004-4221.2016.09.012

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Abstract

Objective To compare the dosimetric data between preoperative plans and postoperative verification in computed tomography (CT) image-guided and 3D printed template-assisted 125-iodine (¹²⁵I) seed implantation for recurrent pelvic tumor, and to explore of the accuracy of the technology in treatment planning. Methods A total of 12 patients with recurrent pelvic tumor who received CT image-guided and 3D printed template-assisted ¹²⁵I seed implantation in our hospital from 2015 to 2016 were enrolled as subjects. ¹²⁵I seeds with a prescribed dose of 110-150 Gy were implanted in 15 lesions. Twelve 3D printed templates were designed and produced for 15 treatment areas. Comparison of the dosimetric parameters between postoperative verification and preoperative plans was made by paired t-test. Results The mean D₉₀, mPD, V₁₀₀, V₁₅₀, and V₂₀₀ were 137.4 Gy, 74.4 Gy, 90.1%, 58.7%, and 34.4%, respectively, in postoperative verification and 140.2 Gy, 61.1 Gy, 91.8%, 64.3%, and 36.7%, respectively, in preoperative plans (P=0.153,0.024,0.028,0.003,and 0.302). The conformity index of gross tumor volume was slightly reduced after operation (0.68 vs. 0.69,P=0.437). The external volume index increased after treatment (34.2% vs. 30.5%, P=0.530). Conclusions 3D printed template provides accurate positioning and orientation for treating recurrent pelvic tumor. All main indices of the actual dose distribution in postoperative verification meet the expectation of the preoperative plan, indicating satisfactory treatment accuracy.

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	Articles by authors
	Jiang Yuliang
	Wang Hao
	Ji Zhe
	Guo Fuxin
	Sun Haitao
	Fan Jinghong
	Zhang Lujing
	Tian Suqing
	Wang Junjie

Key words： Three-dimensional printing Template Dosimetry Neoplasms recurrence pelvic/seeds implantation

Received: 05 April 2016

Corresponding Authors: Wang Junjie

Cite this article:

Jiang Yuliang,Wang Hao,Ji Zhe et al. Computed tomography image-guided and personalized 3D printed template-assisted 125-iodine seed implantation for recurrent pelvic tumor:a dosimetric study[J]. Chinese Journal of Radiation Oncology, 2016, 25(9): 959-964.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2016.09.012 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2016/V25/I9/959

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