Abstract Objective To investigate the feasibility of dose verification of intensity modulated planning of helical tomotherapy (HT) using three-dimensional semiconductor array (Delta4) and find a more time-consuming and accurate method to validate the delivery dose. Methods Delta4 detector array was used to verify the HT plan dose distribution of 10 patients. The precise setup of detector array was guided and registered by MVCT imaging. After the implementation of delivery, the measured dose distributions on the corresponding planes were compared with those calculated by the treatment planning system (TPS). According to the different acceptance criteria combination of dose difference or distance to agreement at different threshold level including 3%/2 mm, 3%/3 mm, 3%/4 mm, 3%/5 mm at TH5, TH10, TH20, TH30, TH70, TH90, the γ analysis method was utilized to evaluate the dose verification. Results The dose distribution measured by the Delta4 was well consistent with that calculated by the TPS. The mean γpassing rates were all above 94.89%. Conclusions Delta4 detector array can get satisfying results when used in HT plan dose verification and is a viable tool to replace traditional film dosimetry system in clinical quality assurance work.
[1] Mackie TR, Holmes T, Swerdloff S, et al. Tomotherapy:a new concept for the delivery of conformal radiotherapy. Med Phys,1993,20:1709-1719. [2] Mackie TR, Balog J, Ruchala K, et al. Tomotherapy. Semin Radiat Oncol,1999,9:108-117. [3] Yang JN, Mackie TR, Reckwerdt P, et al. An investigation of tomotherapy beam delivery. Med Phys,1997,24:425-436. [4] Bortfeld T, Webb S. Single-Arc IMRT? Phys Med Biol,2009,54:9-20. [5] Saminathan S, Manickan R, Chandraraj V, et al. Dosimetric study of 2D ion chamber array matrix for the modern radiotherapy treatment verification. J Appl Clin Med Phys,2010,11:116-127. [6] Herzen J, Todorovic M, Cremers F, et al. Dosimetric evaluation of a 2D pixel ionization chamber for implementation in clinical routine. Phys Med Biol,2007,52:1197-1208. [7] Woo M, Nico A. Using a matrix detector for rotational delivery QA. Med Phys,2007,34:2502. [8] Chandraraj V, Stathakis S, Manickam R, et al. Comparison of four commercial devices for RapidArc and sliding window IMRT QA. J Appl Clin Med Phys,2011,12:338-349. [9] Feygelman V, Opp D, Javedan K, et al. Evaluation of a 3D diode array dosimeter for helical tomotherapy delivery QA. Med Dosim,2010,35:324-329. [10] Bedford JL, Lee YK, Wai P, et al. Evaluation of the Delta4 phantom for IMRT and VMAT verification. Phys Med Biol,2009,54:167-176. [11] Low DA, Dempsey JF. Evaluation of the gamma dose distribution comparison method. Med Phys,2003,30:2455-2464. [12] Geurts M, Gonzalez J, Serrano-Ojeda P. Longitudinal study using a diode phantom for helical tomotherapy IMRT QA. Med Phys,2009,36:4977-4983.4.