[1] Overgaard M,Hansen PS,Overgaard J,et al. Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial. N Engl J Med,1997,337:949-955. [2] Overgaard M,Jensen MB,Overgaard J,et al. Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial.Lancet,1999,353:1641-1648. [3] Ragaz J,Olivotto IA,Spinelli JJ,et al. Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trial. J Natl Cancer Inst,2005,97:116-126. [4] Floyd SR,Taghian AG.Post-mastectomy radiation in large node-negative breast tumors: does size really matter? Radiother Oncol,2009,91:33-37. [5] Helint M,Blomqvist C,Heikkil P,et al. Post-mastectomy radiotherapy in pT3N0M0 breast cancer: is it needed Radiother Oncol,1999,52:213-217. [6] Taghian AG,Jeong JH,Mamounas EP,et al. Low locoregional recurrence rate among node-negative breast cancer patients with tumors 5 cm or larger treated by mastectomy,with or without adjuvant systemic therapy and without radiotherapy: results from five national surgical adjuvant breast and bowel project randomized clinical trials. J Clin Oncol,2006,24:3927-3932. [7] Early breast cancer trialists′ collaborative group(EBCTCG).Comparisons between different poly chemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100000 women in 123 randomised trials. Lancet,2012,379:432-444.