肿瘤热疗生物学机制研究进展

doi:10.3760/cma.j.cn113030-20210227-00083

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Abstract In recent years, tumor hyperthermia has become a hot research topic as an adjuvant therapy to traditional tumor therapy. Hyperthermia can directly induce tumor cell necrosis or apoptosis, or inhibit tumor progression by destroying tumor blood vessels. Meantime, it can also activate the response of immune cells and cytokines in the immune system of the host, thereby regulating the immune state of tumor microenvironment. Multiple combined effects influence the tumor progression. A thorough understanding of the biological mechanism of hyperthermia is beneficial to the development of novel therapeutic methods. In this paper, the biological mechanism of hyperthermia in killing tumors was mainly reviewed.

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	Articles by authors
	Shen Pei
	Zhou Xuexiao
	Shi Fan
	Wang Shengzhi

Key words： Neoplasm/hyperthermia Immune mechanism Apoptosis Tumor microenvironment

Received: 27 February 2021

Corresponding Authors: Wang Shengzhi, Email:Wangsz916@163.com

Cite this article:

Shen Pei,Zhou Xuexiao,Shi Fan et al. Research progress on biological mechanism of tumor hyperthermia[J]. Chinese Journal of Radiation Oncology, 2021, 30(12): 1340-1344.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.cn113030-20210227-00083 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2021/V30/I12/1340

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