双靶区断层治疗图像引导范围对放疗精度的影响

doi:10.3760/cma.j.cn113030-20190917-00007

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Abstract Objective To analyze the impacts of different registration ranges on the accuracy of multiple metastases treated with helical tomotherapy. Methods According to the locations of target volumes, 28 patients with multiple metastases were divided into the head/chest group (n= 15) and the chest/pelvis group (n= 13). The CT and MVCT images acquired in first fraction were studied and compared in two groups, which were captured and matched with different registration ranges (all targets/the targets in proximity to the head/ the targets in proximity to the foot). The CTV_MVCT volume coverage rate (CR) under the matched target volumes,the dice similarity coefficient (DSC) between the CTV_CT and CTV_MVCT, and the position deviation of the CTV geometric center were compared. Results We observed similar results in the head/chest group and chest/pelvis group. Specifically, there was no significant difference in the CR, DSC and geometric center deviation between the two target regions when registered with all targets (P>0.05). Regarding single target region registration, the DSC and geometric center deviation of this target were significantly superior to the other non-registered target (P< 0.05). To a single target, the CR, DSC, and geometric center deviation obtained with registration presented the best performance, which was significantly greater than these parameters obtained with all targets registration, while the other side target area obtained the worst results (P< 0.05). Conclusions Registration of one target region may reduce the accuracy of other non-registered targets. We recommend that the image guidance ranges for multiple metastases treated with tomotherapy should include all target regions or independent registrations for different targets.

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	Articles by authors
	Liu Hui
	Peng Yinglin
	Sun Wenzhao
	He Huilang
	Zhou Linghong

Key words： Helical tomotherapy Multiple metastases Image registration

Received: 17 September 2019

Corresponding Authors: Zhou Linghong,Email:smart@smu.edu.cn

Cite this article:

Liu Hui,Peng Yinglin,Sun Wenzhao et al. Impacts of different registration ranges on the accuracy of multiple metastases treated with tomotherapy[J]. Chinese Journal of Radiation Oncology, 2020, 29(5): 354-357.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.cn113030-20190917-00007 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2020/V29/I5/354

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