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沉默STAT3表达对口腔舌鳞癌细胞生长及放射敏感性的影响及其机制 |
赵媛, 王姝, 吕继连, 韶波 |
450007 郑州大学附属郑州市中心医院(赵媛、吕继连) 010050 呼和浩特,内蒙古医科大学附属医院(王姝) 010020 呼和浩特,内蒙古自治区人民医院(韶波) |
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收稿日期: 2017-10-20
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基金资助:河南省医学科技攻关计划项目(201702307) |
通讯作者:
韶波
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[1] Pan Y,Zhou F,Zhang R,et al. Stat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo-and radio-sensitivity in nasopharyngeal carcinoma[J].PloS One,2013,8(1):e54565.DOI:10.1371/journal.pone.0054565. [2] 刘彬,胡晨曦,刘亮,等.STAT-3介导的非依赖VEGFR-2通路对NSCLC细胞放射敏感性影响的研究[J].中华放射肿瘤学杂志,2017,26(8):938-944.DOI:10.3760/cma.j.issn.1004-4221.2017.08.019. Liu B,Hu CX,Liu L,et al. Effect of STAT-3-mediated non-dependent VEGFR-2 pathway on radiosensitivity of non-small cell lung cancer cells[J].Chine J Radiat Oncol,2017,26(8):938-944.DOI:10.3760/cma.j.issn.1004-4221.2017.08.019. [3] 黄媛媛,周旋,刘爱芹,等.信号传导与转录活化因子3抑制剂 WP1066影响人舌鳞状细胞癌增殖与凋亡的研究[J].中华口腔医学杂志,2014(5):308-313.DOI:10.3760/cma.j.issn.1002-0098.2014.05.014. Huang Y,Zhou X,Liu A,et al. Signal transducer and activator of transcription-3 inhibitor WP1066 affects human tongue squamous cell carcinoma proliferation and apoptosis in vitro and in vivo[J].Chin J Stomatol,2014,49(5):308-313.DOI:10.3760/cma.j.issn.1002-0098.2014.05.014. [4] 孙亚敬,路秀英,李晓明.联合阻断Stat3和HIF-1α对低氧条件下喉癌细胞放化疗的增敏作用[J].临床耳鼻咽喉头颈外科杂志,2015,29(4):352-356.DOI:10.13201/j.issn.1001-1781.2015.04.015. Sun YJ,Lu XY,Li XM.Combined inhibition of Stat3 and HIF-1α for enhancement of radio-and chemo-sensitivity in laryngeal squamous cell carcinoma[J].J Clin Otolaryngol Head Neck Surg,2015,29(4):352-356.DOI:10.13201/j.issn.1001-1781.2015.04.015. [5] Ohnishi Y,Watanabe M,Wato M,et al. CyclinD1 expression is correlated with cell differentiation and cell proliferation in oral squamous cell carcinomas[J].Oncol Lett,2014,7(4):1123-1127.DOI:10.3892/ol.2014.1880. [6] Xiong L,Tang Y,Liu Z,et al. BCL-2 inhibition impairs mitochondrial function and targets oral tongue squamous cell carcinoma[J].Springerplus,2016,5(1):16-26.DOI:10.1186/s40064-016-3310-2. [7] Fasanaro E,Staffieri C,Cappellesso R,et al. Prognostic Significance of Serine-Phosphorylated STAT3 Expression in pT1-T2 Oral Tongue Carcinoma[J].Clin Exper Otorhinolaryngol,2015,8(3):275-280.DOI:10.3342/ceo.2015.8.3.275. |
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