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金纳米颗粒在肿瘤放射增敏中的相关研究进展
赵宁,傅深
200233 上海,复旦大学附属肿瘤医院放射治疗中心 复旦大学上海医学院肿瘤学系
Research advances in gold nanoparticle-mediated tumor radiosensitization
Zhao Ning,Fu Shen
Department of Radiation Oncology,Fudan University Shanghai Cancer Center,Department of Oncology,Shanghai Medical College,Fudan University,Shanghai 200233,China
Abstract： Nanotechnology has been extensively applied in the diagnosis and treatment of cancer, and is currently a major focus of research worldwide. Among the various nanomaterials, gold nanoparticles (GNPs) are of particular interest to many researchers due to their superior properties of low cytotoxicity, good biocompatibility, and preferential accumulation in tumors (the “enhanced permeability and retention” effect), which in turn gives GNPs a potential application in cancer diagnostics, imaging, photothermal therapy, and radiotherapy. Many published studies have shown that GNPs can be used as a new ideal radiosensitizer, and therefore understanding the radiosensitizing effects of GNPs both in vitro and in vivo will be of great significance in the clinical translation of nanomedicine.
Zhao Ning,Fu Shen. Research advances in gold nanoparticle-mediated tumor radiosensitization[J]. Chinese Journal of Radiation Oncology, 2017, 26(7): 838-841.
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2017, Vol. 26 
