Abstract： The Medline and CNKI databases were searched with the key words of “radiation-induced myocardial damage, damage pathway, pathogenesis, and intervention”, and 37 articles were obtained. The pathogenesis of radiation-induced myocardial damage may be related to various mechanisms such as oxidative stress, transforming growth factor-β, renin-angiotensin system, mast cells, and endothelial dysfunction. The pathogenesis of radiation-induced myocardial damage is a complex process involving various mechanisms, and currently, there are ongoing studies on the cellular and molecular mechanisms involved in its pathogenesis and interventions.
Wu Yajing,Wang Jun,Wang Yi. Research advances in the pathogenesis of radiation-induced myocardial damage[J]. Chinese Journal of Radiation Oncology, 2016, 25(6): 657-660.
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