The role of transoralsonography guiding fine-needle aspiration biopsy in the diagnosis of retropharyngeal or parapharyngeal masses identified on the images of treated patients with malignant carcinoma
Zhang Youwang*, Huang Yafang, Ying Hongmei, Kong lin, Wu Yongru, Du Chengrun, Hu Chaosu
*Department of Radiation Oncology, Cancer Hospital of Fudan University;Department of Oncology, Shanghai Medical College of Fudan University;Shanghai 200032, China
Abstract：Objective To investigate the role of transoralsonography guiding fine-needle aspiration biopsy in the diagnosis of retropharyngeal or parapharyngeal masses identified on the CT, MRI or PET-CT images of treated patients with malignant carcinoma. Methods From 2002 to 2013,this study recruited fifty-five patients with a history of cancer, of which 50 were treated with radiation treatment, including 46 nasopharyngeal carcinoma, 3 esophagus squamous cell carcinoma and1 lung apex carcinoma. There were 4 patients with a history of 1 thyroid papillary carcinoma, 1 buccal mucosa squamous cell carcinoma,1 glottis squamous cell carcinoma and 1 sigmoid colon adenocarcinoma treated with surgery. The rest one patient with nasal olfactory neuroblastoma was treated by postoperative radiation. The enlarged retropharyngeal lymph nodes in 44 cases and parapharyngeal masses in 10 cases were identified on CT or MRI imges. The enlarged retropharyngeal lymph node in the rest case was identified on PET-CT. With transoral ultrasound examination, all lesions were with hypo-intensity echo. Cystic areas were noted on occasion. Biopsy was performed in all cases. Results After cytology examination, carcinoma cells were detected in 37 retropharyngeal lymph nodes, with a detection rate of 82%(37/45). In the 10 parapharyngeal masses, carcinoma cells were detected in 3 lesions, with a detection rate of 30%. Conclusions Transor alsonography guiding fine-needle aspiration biopsy can be useful in the cytopathology diagnosis of retropharyngeal or parapharyngeal masses identified on the CT, MRI or PET-CT images of treated patients with malignant carcinoma,which facilitates, early diagnosis and treatment for patients.
Zhang Youwang*,Huang Yafang,Ying Hongmei et al. The role of transoralsonography guiding fine-needle aspiration biopsy in the diagnosis of retropharyngeal or parapharyngeal masses identified on the images of treated patients with malignant carcinoma[J]. Chinese Journal of Radiation Oncology, 2015, 24(4): 427-430.
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2015, Vol. 24 
