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中华放射肿瘤学杂志
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中华放射肿瘤学杂志  2014, Vol. 23 Issue (4): 340-343    DOI: 10.3760/cma.j.issn.1004-4221.2014.04.016
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千伏级CBCT引导鼻咽癌IMRT中不同图像配准方式比较
李晓玉, 周继丹, 钟仁明, 李安, 李帅
610041 成都,四川大学华西医院放射物理技术中心
Compare the registration results with different registration methods in cone beam CT guided radiotherapy for nasopharyngeal carcinoma
Li Xiaoyu, Zhou Jidan,Zhong Renming, Li An, Li Shuai
Centro of Radiophysical and Technology, West China Hospital, Sichuan University, Chengdu 610041, China
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摘要 目的 比较千伏级CBCT引导下鼻咽癌IMRT中不同图像配准方式对配准结果的影响。方法 搜集2012—2013年24例鼻咽癌IMRT患者560次治疗前初次摆位的千伏级CBCT图像做离线配准分析。分别选取骨与灰度的平移误差加旋转误差配准方式(BoneT+R与GreyT+R),以及单纯灰度平移误差配准方式(GreyT),并对配准结果行配对t检验。结果 BoneT+R在左右、上下、前后方向的靶区中心平移误差与旋转误差分别为(-0.11±1.35)、(0.40±2.09)、(0.95±1.56) mm与1.06°±0.67°、0.01°±1.28°、0.92°±1.00°;GreyT+R的平移误差与旋转误差分别为(-0.02±1.06)、(0.68±1.92)、(0.81±1.46) mm与0.85°±0.61°、-0.05°±1.32°、0.91°±0.72°;GreyT的平移误差分别为(0.58±1.02)、(0.52±1.89)、(0.44±1.43) mm。除BoneT+R与GreyT+R旋转误差在上下、前后方向上相近外(P=0.05、0.62),其余均不同(P=0.00~0.01)。结论 用千伏级CBCT引导鼻咽癌IMRT时,在三维方向上的配准结果因图像配准方式不同而有差别。选择自动配准方式时,若要纠正旋转误差建议选择GreyT+R方式;不纠正旋转误差时建议可先选择GreyT+R方式观察有否旋转误差>2°或3°(视各放疗中心要求而定),若有则需重新摆位,若无则重新选择GreyT方式,必要时辅以手动修正。
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李晓玉
周继丹
钟仁明
李安
李帅
关键词 鼻咽肿瘤/放射疗法体层摄影术X线计算机锥形束图像配准    
Abstract:Objective To compare the results of three different registration methods in the kilovolt CBCT guided IMRT for nasopharyngeal cancer (NPC). Methods Total 560 CBCT images of 24 NPC patients who received kilovolt CBCT guided IMRT were analyzed off line. Three registration methods were used for alignment between CBCT and planning CT, including translational and rotational errors for bone and grey (BoneT+R,GreyT+R),only translational errors for grey (GreyT). The registration results were analyzed by mean paired t-test respectively. Results With method BoneT+R, the translational errors on x, y and z axes were (-0.11±1.35) mm,(0.40±2.09) mm and (0.95±1.56) mm and the rotational errors were 1.06°±0.67°, 0.01°±1.28° and 0.92°±1.00° respectively. With GreyT+R, the translational errors on x, y and z axes were (-0.02±1.06) mm,(0.68±1.92) mm and (0.81±1.46) mm and the rotational errors were 0.85°±0.61°, -0.05°±1.32° and 0.91°±0.72° respectively. With GreyT, the translational errors on x, y and z axes were (0.58±1.02),( 0.52±1.89) and (0.44±1.43) mm. The results of compared mean t-test for different registration methods groups have significant difference (P=0.00—0.01) except for the rotational errors on y and z axes between BoneT+R and GreyT+R (P=0.05,0.62). ConclusionsThere have different alignment errors when different registration methods used for NPC kilovolt CBCT guided radiotherapy. If there have correct methods for rotation errors, GreyT+R registration method may be a better choice. In opposite, GreyT+R registration method would be used firstly to verify whether the rotational error>2°or 3°. If the rotational error>2°or 3°,the patient should be re-setup. If not,according to these alignment results, the GreyT method, manual method would be used to compensate the translational errors.
Key words Nasopharyngeal neoplasms/radiotherapy    Tomography, X-ray computed, cone-beam    Image registration   
收稿日期: 2013-06-28     
引用本文:   
李晓玉,周继丹,钟仁明等. 千伏级CBCT引导鼻咽癌IMRT中不同图像配准方式比较[J]. 中华放射肿瘤学杂志, 2014, 23(4): 340-343.
Li Xiaoyu,Zhou Jidan,Zhong Renming et al. Compare the registration results with different registration methods in cone beam CT guided radiotherapy for nasopharyngeal carcinoma[J]. Chinese Journal of Radiation Oncology, 2014, 23(4): 340-343.
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