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肺内孤立灶大体肿瘤体积CT不同扫描方式比较
尚东平, 王玮, 李建彬, 王云刚, 张英杰, 李延持, 杜君
250117 济南,山东省放射肿瘤学重点实验室山东省肿瘤医院和研究所放疗科
A comparison of the different CT scanning modes on the GTV delineation of the solitary pulmonary lesion
SHANG Dong-ping, WANG Wei, LI Jian-bin, WANG Yun-gang, ZHANG Ying-jie, LI Yan-chi, DU Jun
Department of Radiation Oncology, Shandong Tumor Hospital and Institute;Shandong Province Key Laboratory of Radiation Oncology;Ji′nan 250117,China Corresponding author:LI Jian-bin, Email:lijianbin@msn.com
Abstract：Objective To explore the influence of the CT scanning mode on the gross tumor volume (GTV) delineation of solitary pulmonary lesion (SPL), and to evaluate the feasibility of the spiral CT scan in CT simulation. Methods Sixteen patients with SPL underwent axial scan, spiral scan during free breathing. Compare the target position, volume between GTVs and GTVA (paired t-test). The matching index (MI) between GTVs and GTVA and correlations between MI and the tumor volume were calculated (bivariate correlation analysis). Results GTVs and GTVA volume was 8.95 cm3 and 9.38 cm3(t=0.43,P=0.667), respectively. The centroid position for GTVs and GTVA in x,y and z axises were 6.80 cm and 6.81 cm (t=0.27,P=0.794), 36.19 cm and 36.05 cm (t=0.37,P=0.717), and 4.99 cm and 4.96 cm (t=0.65,P=0.526),respectively. There were also no statistically significant difference in the distance between the centroidal position and origin of coordinates for GTVs and GTVA (38.31 cm∶38.23 cm,t=0.47,P=0.646). MI between GTVs and GTVA was 0.36(range 0－0.77), correlated with the tumor volume (r=0.587, P=0.017). Conclusions There was no significant difference between the axial scan and spiral scan in the GTV volume and position for SPL, but MI between GTVs and GTVA were small. A correlation was found for the MI between GTVs and GTVA with the tumor volume. Spiral CT scan was more timesaving, and was feasible in CT simulation scan.
SHANG Dong-ping,WANG Wei,LI Jian-bin et al. A comparison of the different CT scanning modes on the GTV delineation of the solitary pulmonary lesion[J]. Chinese Journal of Radiation Oncology, 2012, 21(5): 436-438.
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