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肿瘤热疗生物学机制研究进展
沈佩1,2, 周学筱1,2, 石凡1,2, 王升志2
1青岛大学口腔医学院 266003; 2青岛大学附属烟台毓璜顶医院口腔科 264000
Research progress on biological mechanism of tumor hyperthermia
Shen Pei1,2, Zhou Xuexiao1,2, Shi Fan1,2, Wang Shengzhi2
1School of Stomatology of Qingdao University, Qingdao 266003, China; 2Department of Oral and Maxillofacial Surgery, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai 264000, China
Abstract：In recent years, tumor hyperthermia has become a hot research topic as an adjuvant therapy to traditional tumor therapy. Hyperthermia can directly induce tumor cell necrosis or apoptosis, or inhibit tumor progression by destroying tumor blood vessels. Meantime, it can also activate the response of immune cells and cytokines in the immune system of the host, thereby regulating the immune state of tumor microenvironment. Multiple combined effects influence the tumor progression. A thorough understanding of the biological mechanism of hyperthermia is beneficial to the development of novel therapeutic methods. In this paper, the biological mechanism of hyperthermia in killing tumors was mainly reviewed.
Shen Pei,Zhou Xuexiao,Shi Fan et al. Research progress on biological mechanism of tumor hyperthermia[J]. Chinese Journal of Radiation Oncology, 2021, 30(12): 1340-1344.
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2021, Vol. 30 
