非小细胞肺癌立体定向放疗所致放射性肺炎相关因素研究进展

doi:10.3760/cma.j.cn113030-20200531-00287

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摘要立体定向放疗现已成为早期非小细胞肺癌治疗的重要选择。放射性肺炎是早期非小细胞肺癌患者立体定向放疗后主要不良反应。患者因素、肿瘤因素、治疗因素等都与早期非小细胞肺癌患者立体定向放疗后放射性肺炎的发生相关。近年来的相关研究进一步明确了这些因素与放射性肺炎的关联,而且对与RP发生相关的预测因素进行了进一步探讨。本文对近年来的相关研究结果进行了综述。

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	付守鹏
	张英杰
	李建彬

关键词 ：放射性肺炎, 危险因素, 癌,非小细胞肺/立体定向放射疗法

Abstract：Stereotactic body radiotherapy (SBRT/SABR) has become an important option in the treatment of early non-small-cell lung cancer (NSCLC). Radiation pneumonitis (RP) is the main side effect of early NSCLC patients after SBRT/SABR. Patient factors, tumor factors and treatment factors are all associated with the occurrence of RP in early NSCLC patients after SBRT/SABR. In recent years, relevant studies have further clarified the relationship between these factors and RP. In addition, the prediction factors related to RP occurrence are further discussed. In this paper, relevant research progresses in recent years were reviewed.

Key words： Radiation pneumonitis Risk factor Carcinoma, non-small-cell lung/stereotactic body radiotherapy

收稿日期: 2020-05-31

ZTFLH:

基金资助:国家自然基金青年基金项目(81201735);山东省重点研发计划项目(2015GSF118011)

通讯作者: 张英杰,Email:761094890@qq.com

引用本文:

付守鹏,张英杰,李建彬. 非小细胞肺癌立体定向放疗所致放射性肺炎相关因素研究进展[J]. 中华放射肿瘤学杂志, 2021, 30(12): 1330-1334.

Fu Shoupeng,Zhang Yingjie,Li Jianbin. Research progress on risk factors of radiation pneumonitis caused by stereotactic body radiotherapy for non-small-cell lung cancer[J]. Chinese Journal of Radiation Oncology, 2021, 30(12): 1330-1334.

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