[an error occurred while processing this directive]|[an error occurred while processing this directive]
主动呼吸控制与自由呼吸配合bodyfix固定装置用于胸部肿瘤SBRT对比研究
应微, 张德康
四川省肿瘤医院放疗中心,成都 610041
Preliminary comparative study of active breathing coordinator and free breathing combined with bodyfix fixation device in stereotactic radiotherapy of thoracic tumors
Ying Wei, Zhang Dekang
Radiotherapy Center of Sichuan Cancer Hospital, Chengdu 610041, China
Abstract：Objective To compare the difference between active breathing coordinator (ABC) technique and free breathing (FB) mode combined with bodyfix stereotactic radiotherapy (SBRT) for chest tumors. Methods 40 thoracic tumor patients receiving SBRT were randomly selected and divided into the ABC technique group and FB model group. After fixation with bodyfix fixing devices in two groups, cone-beam CT (CBCT) scan images before each SBRT were matched with the plan reference images. The setup errors in the left-right (LR), superior-inferior (SI) and anterior-post (AP) directions were obtained. Then, the setup errors were corrected. SBRT was performed and split intra-fraction CBCT was conducted simultaneously, which was repeated until the end of treatment. Results In the ABC technique group, the setup errors in the LR, SI and AP directions were (0.25±0.21) cm,(0.28±0.21) cm, and (0.21±0.24) cm, significantly less compared with (0.31±0.22) cm,(0.32±0.21) cm and (0.37±0.23) cm in the FB model group (all P<0.05). The V30Gy of the heart, the V20Gy and V30Gy of the lung in the ABC technique group were significantly less than those in the FB model group (0.31%∶7.35%;24.5%∶32.9%;19.5%∶25.8%, all P<0.05). Conclusions ABC technique combined with bodyfix fixation device may be superior to FB mode in SBRT for chest tumors, which remains to be validated by subsequent studies with large samples.
Ying Wei,Zhang Dekang. Preliminary comparative study of active breathing coordinator and free breathing combined with bodyfix fixation device in stereotactic radiotherapy of thoracic tumors[J]. Chinese Journal of Radiation Oncology, 2021, 30(7): 717-720.
[1] 梁军,张涛,张寅,等. 肺癌锥形束CT图像不同配准方式的误差分析[J]. 中华放射肿瘤学杂志,2011, 20(2):106-108. DOI:10.3760/cma.j.issn.1004-4221.2011.02.007. Liang J, Zhang T, Zhang Y, et al. Cone-beam CT imagine registration of lung cancer[J]. Chin J Radiat Oncol, 2011, 20(2):106-108. DOI:10.3760/cma.j.issn.1004-4221.2011.02.007. [2] Dzierma Y, Nuesken FG, Fleckenstein J, et al. Visualisation of respiratory tumour motion and co-moving isodose lines in the context of respiratory gating,IMRT and flattening-filter-free beams[J]. PLoS One, 2013, 8(1):e53799. DOI:10.1371/journal.pone.0053799. [3] Shirato H, Onimaru R, Ishikawa M, et al. Real-time 4-D radiotherapy for lung cancer[J]. Cancer Sci, 2012, 103(1):1-6. DOI:10.1111/j.1349-7006.2011.02114.x. [4] Fiocchi S, Liorni I, Parazzini M, et al.Assessment of foetal exposure to the homogeneous magnetic field harmonic spectrum generated by electricity transmission and distribution networks[J]. Int J Environ Res Public Health, 2015, 12(4):3667-3690. DOI:10.3390/ijerph120403667. [5] Stroom JC, Heijmen BJ. Geometrical uncertainties, radiotherapy planning margins, and the ICRU-62 report[J]. Radiother Oncol, 2002, 64(1):75-83. DOI:10.1016/s0167-8140(02)00140-8. [6] 邹喜,陈金梅,洪金省,等. 非小细胞肺癌肿瘤体积大小对调强放射治疗肺剂量体积参数的影响[J]. 中南大学学报(医学版), 2017, 42(4):413-418. DOI:10.11817/j.issn.1672-7347.2017.04.008. Zou X, Chen JM, Hong JS, et al. Effect of tumor volume on pulmonary dose-volume parameter by intensity-modulated radiation therapy in non-small cell lung cancer[J]. J Cent South Uni (Med ed), 2017, 42(4):413-418. DOI:10.11817/j.issn.1672-7347.2017.04.008. [7] Tsurugai Y, Takeda A, Sanuki N, et al. Stereotactic body radiotherapy for patients with non-small-cell lung cancer using RapidArc delivery and a steep dose gradient prescription of 60% isodose line of maximum dose fitting to the planning target volume[J]. J Radiat Res, 2019, 60(3):364-370. DOI:10.1093/jrr/rry112. [8] Stam B, Grills IS, Kwint M, et al. SBRT for central tumors in early stage NSCLC patients[J]. Int J Rad-iat Oncol Biol Phys, 2017, 99(2):S17. DOI:10.1016/j.ijrobp.2017.06.054. [9] 罗国民,王瑾. 肺癌精确放疗的误差及其控制[J]. 中国肿瘤临床, 2014, 41(4):276-279. DOI:10.3969/j.issn.1000-8179.20121856. Luo GM, Wang J. Evolution and control of errors in precision radiotherapy of lung cancer[J]. Chin J Clin Oncol, 2014, 41(4):276-279. DOI:10.3969/j.issn.1000-8179.20121856. [10] Kim J, Lee H, Wu HG, et al. Development of patient-controlled respiratory gating system based on visual guidance for magnetic-resonance image-guided radiation therapy[J]. Med Phys, 2017, 44(9):4838-4846. DOI:10.1002/mp.12447. [11] Wong JW, Sharpe MB, Jaffray DA, et al. The use of active breathing control (ABC) to reduce margin for breathing motion[J]. Int J Radiat Oncol Bionl Phys, 1999, 44(4):911-919. DOI:10.1016/s0360-3016(99)00056-5. [12] Remouchamps VM, Vicini FA, Sharpe MB, et al. Significant reductions in heart and lung doses using deep inspiration breath hold with active breathing control and intensity-modulated radiation therapy for patients treated with locoregional breast irradiation[J]. Int J Radiat Oncol Biol Phys, 2003, 55(2):392-406. DOI:10.1016/S0360-3016(02)04143-3. [13] 麦海涛,岑铨华,李成毅. 新型精确放射治疗肿瘤靶区呼吸控制系统的研制[J]. 中国医学装备,2016, 13(5):5-8. DOI:10.3969/J. ISSN.1672-8270.2016.05.002. Mai HT, Cen QH, Li CY. Development of a new breathing control system of tumor target for precision radiotherapy[J]. Chin Med Equip, 2016, 13(5):5-8. DOI:10.3969/J. ISSN.1672-8270.2016.05.002. [14] Wu B, Ricchetti F, Sanguineti G, et al. Patient geometry-driven information retrieval for IMRT treatment plan quality control[J]. Med Phys, 2009, 36(12):5497-5505. DOI:10.1118/1.3253464. [15] 谭薇薇,周一兵,周军,等. ELEKTA主动呼吸控制技术应用方法分析[J]. 医疗卫生装备,2014, 35(8)::116-118. DOI:10.7687/J. ISSN1003-8868.2014.08.116. Tan WW, Zhou YB, Zhou J, et al. Application method of ELEKTA active breathing control[J]. Chin Med Equip J, 2014, 35(8):116-118. DOI:10.7687/J. ISSN1003-8868.2014.08.116 [16] 杨露,张英杰,李光俊,等. 主动呼吸控制和四维CT技术在肺部肿瘤立体定向放射治疗中的应用[J]. 中华放射医学与防护杂志,2016, 36(9):667-671. DOI:10.3760/cma.j.issn.0254-5098.2016.09.006. Yang L, Zhang YJ, Li GJ, et al. Application of active breathing control (ABC) and four dimensional CT technology in stereotactic radiotherpy of lung tumor[J]. Chin J Radiol Med Protect, 2016,36(9):667-671. DOI:10.3760/cma.j.issn.0254-5098.2016.09.006.
2021, Vol. 30 
