Different receptive fields-based automatic segmentation network for gross target volume and organs at risk of patients with nasopharyngeal carcinoma
Liu Yuliang1, Li Yongbao2, Qi Mengke1, Wu Aiqian1, Lu Xingyu1, Song Ting1, Zhou Linghong1
1School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China; 2Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China
Abstract：Objective To establish an automatic segmentation network based on different receptive fields for gross target volume (GTV) and organs at risk in patients with nasopharyngeal carcinoma. Methods Radiotherapy data of 100 cases of nasopharyngeal carcinoma including CT images and GTV and organs at risk delineated by the physicians were collected. Ninety plans were randomly selected as the training dataset, and the other 10 plans as the validation dataset. Firstly, the images were subject to three data augmentation methods including center cropping, vertical flipping and rotation (-30°to 30°), and then input into MA_net networks proposed in this study for training. The model performance of networks was assessed by the number of network parameters (NP), floating-point number (FPN), the running memory (RM) and Dice index (DI), and eventually compared with DeeplabV3+, PSP_net, UNet++ and U_Net networks. Results When the input image was in the size of 240×240, MA_net had a NP of 23.20%, 20.10%, 25.55% and 27.11% of these 4 networks, 50.02%, 19.86%, 6.37% and 13.44% for the FPN, 40.63%, 23.60%, 11.58% and 14.99% for the RM, respectively. For the DI of GTV, MA_net was 1.16%, 2.28%, 1.27% and 3.59% higher than these 4 networks. For the average DI of GTV and OAR, MA_net was 0.16%, 1.37%, 0.30% and 0.97% higher than these 4 networks. Conclusion Compared with those four networks, the proposed MA_net network has slightly higher Dice index with fewer parameters, lower FPN and smaller RM.
Liu Yuliang,Li Yongbao,Qi Mengke et al. Different receptive fields-based automatic segmentation network for gross target volume and organs at risk of patients with nasopharyngeal carcinoma[J]. Chinese Journal of Radiation Oncology, 2021, 30(5): 468-474.
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2021, Vol. 30 
