Research progress on radiotherapy combined with PD-1/PD-L1 inhibitors in the treatment of breast cancer
Jiang Jie1,2, Huang Wei2
1Weifang Medical University, Weifang 261053, China; 2Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji'nan 250117, China
Abstract:Radiotherapy has been proven to enhance tumor-specific immune response and provide targets for immune drugs. Immune checkpoint inhibitors represented by PD-1/PD-L1 combined with radiotherapy can enhance anti-tumor activity and exert abscopal effect. In this article, research progress on the basic study and clinical trials and challenges of radiotherapy combined with PD-1/PD-L1 inhibitors in the treatment of breast cancer were reviewed.
Jiang Jie,Huang Wei. Research progress on radiotherapy combined with PD-1/PD-L1 inhibitors in the treatment of breast cancer[J]. Chinese Journal of Radiation Oncology, 2021, 30(4): 424-428.
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