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MR引导的放疗系统临床应用
刘镖水, 郭旋, 丁寿亮, 王彬, 李永宝, 夏云飞, 欧阳翼, 黄晓延, 林承光
中山大学肿瘤防治中心放疗科 华南肿瘤学国家重点实验室 肿瘤医学协同创新中心,广州 510060
The clinical application of magnetic resonance-guided radiotherapy
Liu Biaoshui, Guo Xuan, Ding Shouliang, Wang Bin, Li Yongbao, Xia Yunfei, Ouyang Yi, Huang Xiaoyan, Lin Chengguang
State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine,Department of Radiation Oncology,Sun Yat-sen University Cancer Center, Guangzhou 510060, China
Abstract：Objective To investigate the clinical feasibility of the Unity radiotherapy system guided by magnetic resonance imaging. Methods Twenty-four patients were enrolled and received a total of 384 fractions of treatment at Unity system. According to the treatment site, all patients were divided into head-neck, abdomen-thorax, pelvic, spine and limb groups. The patients were set-up without external laser. And then, the time required at different stages in online treatment process and the registration error of each fraction were separately calculated. The geometric deformations of MR images were weekly measured by using MR geometric deformation phantom. At last, the Arccheck was used to perform the dose verification of reference plan, online plan and offline plan. Results The mean duration of radiotherapy in the five groups were 29.1, 27.6, 26.6, 25.6 and 32.0min, respectively. The set-up errors in the left-right, superior-inferior and anterior-posterior direction in the five groups were:head-neck group (0.08±0.06cm, 0.16±0.13cm, 0.08±0.05cm), abdomen-thorax group (0.23±0.18cm, 0.50±0.47cm, 0.12±0.1cm), pelvic group (0.25±0.19cm, 0.32±0.25cm, 0.11±0.09cm), spine group (0.46±0.38cm, 0.26±0.26cm, 0.13±0.07cm) and limb group (0.33±0.30cm, 0.34±0.23cm, 0.08±0.06cm), respectively. In the central region, the geometric deformation of MR was less than 0.3mm, and that of the sphere with a diameter of 500mm was less than 2.1mm. The meanγ pass rate of the reference plan, online plan and offline plan were 97.92%, 97.84% and 94.58%, respectively. Conclusions MR-guided radiotherapy has great potential for clinical application, whereas the process of Unity system is relatively complex. The synergy of different departments has a great impact on the treatment, which needs further optimization.
Liu Biaoshui,Guo Xuan,Ding Shouliang et al. The clinical application of magnetic resonance-guided radiotherapy[J]. Chinese Journal of Radiation Oncology, 2021, 30(2): 134-139.
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2021, Vol. 30 
