Abstract:Objective To explore the feasibility and advantages of different MRI sequences in delineating target volumes in lung cancer with obstructive pneumonia or atelectasis (OC). Methods Fourteen patients with OC underwent CT localization and MRI scan. CT, T1WI, fat suppression T2WI, LAVA, LAVA+C images were collected respectively. CT and MRI images were fused in the treatment planning system, and GTV-p was target delineated on CT and MRI respectively. Results CT showed tumor and OC boundaries in 2 patients, fat suppression T2WI showed tumor and OC boundaries in 10 patients, LAVA showed tumor and OC boundaries in 12 patients, and LAVA+C showed tumor and OC boundaries in 10 patients. Fat suppression T2WI, LAVA, and LAVA+C sequences showed similar resolving ability (P>0.05). The GTV of T2WI, LAVA, and LAVA+C sequences decreased significantly compared with ST-GTV (P<0.05), and T2WI_GTV and LAVA_GTV were similar (P>0.05). The GTV value of LAVA+C was the smallest among all sequences. Conclusions The application of MRI fat compression T2WI, LAVA, and LAVA+C sequences to the radiotherapy target volume delineation in lung cancer patients with OC improved the accuracy, among which the boundary resolution of LAVA was better than that of fat compression T2WI, and LAVA+C showed the best effect on tiny blood vessels.
He Tianyu,Li Sihan,Li Guang. The value of MRI enhanced scan sequence in the radiotherapy target volume delineation in lung cancer with obstructive pneumonia/atelectasis[J]. Chinese Journal of Radiation Oncology, 2020, 29(5): 369-377.
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