Exploration of combined application of three Varian OBI image-guided systems in image-guided radiotherapy for nasopharyngeal cancer
Zhang Bingxin, Shi Xiangli, Liang Guangli, Wang Wei
Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China
Abstract：Objective To compare the comprehensive performance of three Varian on-board image (OBI) image systems (KV-CBCT, KV-planar and MV-EPID) and to explore the value of the combinedapplication of these three systems in daily image-guided radiotherapy for nasopharyngeal cancer. Methods KV-CBCT, KV-planar and MV-EPID scanning and registration were carried out in the left and right/abdominal and back/head and foot direction on human head and neck phantom. The set-up error, registration time, additional radiation dose and image quality of the three systems were compared by F-test. Results KV-CBCT,kV-planar and MV-EPID were scanned for 55 times, respectively, and the set-up errors in the left and right/abdominal and back/head and foot direction of the three image-guided systems were (0.00±5.43)/(-0.02±5.49)/(0.02±5.58)mm,(0.04±5.49)/(0.02±5.56)/(0.02±5.54)mm,(0.02±5.22)/(0.11±5.34)/(-0.04±5.33)mm,respectively (P=0.999,1.000, 0.989). The average time consuming was (200±45) s,(120±36) s and (115±42) s;the additional radiation dose from low to high was kV-planar, KV-CBCT and MV-EPID;the image quality from low to high was MV-EPID, kV-planar and KV-CBCT. Conclusions Three image-guided systems can meet the requirements of image-guided radiotherapy for nasopharyngeal cancer. Based on the overall performance of the three systems, 1 CBCT+4kV planar per week is recommended and EPID should be used as a backup system in daily image-guided radiotherapy for nasopharyngeal cancer. This scheme makes full use of the high image quality of CBCT and the low radiation of kV planar to realize the regular detection of nasopharyngeal cancer volume change and the implementation of high-precision radiotherapy.
Zhang Bingxin,Shi Xiangli,Liang Guangli et al. Exploration of combined application of three Varian OBI image-guided systems in image-guided radiotherapy for nasopharyngeal cancer[J]. Chinese Journal of Radiation Oncology, 2022, 31(4): 365-369.
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