Research progress on target delineation for radiotherapy in hepatocellular carcinoma with
Lin Haimin, Liu Chengxin, Han Dali, Yu Jinming
1Department of Radiation Oncology, Shandong Cancer Hospital affiliated to Shandong University, Ji′nan 250117,China; 2School of Medicine and Life Sciences, University of Ji′nan-Shandong Academy of Medical Science, Ji′nan 250200, China
Abstract：Modern medical imaging techniques, such as computed tomorgraphy (CT), magnetic resonance imaging (MRI) and position emission tomorgraphy/computed tomorgraphy (PET-CT) can accurately delineate the gross target volume (GTV) of hepatocellular carcinoma (HCC). Comparison of postoperative pathological subclinical lesions, imaging and clinical parameters contributes to the precise delineation of clinical target volume (CTV). Moreover, radiotherapy-assisted techniques, such as four-dimensional computed tomography (4DCT), compression of abdomen, active breathing control and respiratory gating, can minimize the internal target volume (ITV). In addition, immobilization with vacuum cushion and body membrane can reduce the set-up error,minimize the planning target volume (PTV) and avoid or decrease the irradiation error or missing irradiation. All these approach can minimize the target volume, elevate the dose and reduce the complications during radiotherapy for HCC. In this article, the research progress on the target delineation for external beam radiotherapy in HCC patients was reviewed.
Lin Haimin,Liu Chengxin,Han Dali et al. Research progress on target delineation for radiotherapy in hepatocellular carcinoma with[J]. Chinese Journal of Radiation Oncology, 2019, 28(7): 551-554.
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2019, Vol. 28 
