Imaging analysis of rectal cancer patients with clinical and pathological complete remission after concurrent chemoradiotherapy
Zhao Jing, Miao Zheng, Ma Jiabin, Hu Ke, Zhong Guangxi, Xiao Yi, Xue Huadan
Department of Oncology, Beijing Shijitan Hospital,Capital Medical University, Beijing 100038,China (Zhao J);
Department Of Radiation Oncology (Miao Z,Ma JH,Hu K),Department of Ultrasound (Zhong GX),Department of General Surgery (Xiao Y),Department Of Radiology (Xue HD),Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730,China
Objective To analyze the imaging data of patients with complete clinical remission (cCR) and postoperative pathological complete remission (pCR) after concurrent chemoradiotherapy, aiming to evaluate the values of MRI and rectal ultrasound in predicting pCR. Methods Clinical data of 42 patients with locally advanced rectal cancer treated with concurrent chemoradiotherapy combined with operation were retrospectively analyzed. The magnetic resonance imaging (MRI), endoscopic ultrasound (EUS) and pathological data were statistically compared between patients with cCR and pCR. Results After concurrent chemoradiotherapy,12 patients obtained cCR and 7 patients achieved pCR.The consistency rate of cCR between MRI and EUS was 3/12(25%), and 4/12(33%) for pCR.The consistency rate of pCR of MRI combined with EUS was 5/12(42%). Conclusion Rectal ultrasound combined with MRI cannot fully predict pCR.More accurate detection approach remains to be explored to evaluate the clinical outcomes of watch-and-wait patients.
Zhao Jing,Miao Zheng,Ma Jiabin et al. Imaging analysis of rectal cancer patients with clinical and pathological complete remission after concurrent chemoradiotherapy[J]. Chinese Journal of Radiation Oncology, 2018, 27(6): 585-587.
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2018, Vol. 27 
