射波刀立体定向放疗中金标利用率统计与弃用原因分析

doi:10.3760/cma.j.issn.1004-4221.2018.03.013

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摘要目的统计射波刀VSI治疗中金标的利用率并分析金标弃用的原因,为金标植入、放疗计划设计和操作提供参考数据。方法 2017年3—8月间植入或粘贴金标患者47人次,植入金标42人次,其中CT引导3D共面模板辅助植入金标32人次,CT引导3D非共面模板辅助植入金标1人次,不使用模板辅助单纯CT引导下植入1人次,超声引导下金标植入8人次。利用射波刀共治疗44人次肿瘤患者,有2人次肿瘤患者金标不能使用改为脊柱追踪,有3人次患者未行射波刀放疗。统计患者在射波刀治疗时使用的金标和弃用金标的数量,得到金标的利用率和弃用率。对弃用金标的原因进行分析并分类统计。结果 44人次患者植入体内和粘贴体表的134颗金标有111颗被使用,利用率为82.8%;弃用23颗,弃用率为17.2%。造成金标弃用的主要因素有刚性误差大(26.1%)、植入金标不符合要求(17.4%)、金标移位(26.1%)、其他因素(30.4%)。结论应用CT引导3D共面或非共面模板辅助植入金标,较单纯CT引导徒手植入和超声引导下植入金标,每次金标植入只需要使用2根穿刺针,单根穿刺针植入2颗金标,减少了穿刺针数目,降低了患者穿刺造成的风险和创伤,降低金标植入手术术后并发症的发生率;多种方式植入的金标在治疗中不是全部都能被使用,会因各种原因造成弃用,因此要在金标植入等环节中考虑到此情况。

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	徐飞
	郭福新
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	江萍
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	姜玉良
	吉喆
	孙海涛
	程程
	王俊杰

关键词 ：肿瘤/立体定向放射疗法, 射波刀, 金标, 利用率

Abstract：Objective To investigate the utilization rate of gold fiducial markers and reasons for abandonment of gold fiducial markers in the CyberKnife VSI System, and to provide reference data for implantation of gold fiducial markers and radiotherapy planning. Methods From March to August, 2017, a total of 47 patients had gold fiducial markers implanted or pasted. In those patients, 42 patients had gold fiducial markers implanted, including 32 receiving computed tomography (CT)-guided 3D-printing coplanar template assisted implantation, 1 receiving CT-guided 3D-printing non-coplanar template assisted implantation, 1 receiving CT-guided implantation, and 8 receiving ultrasound-guided implantation. A total of 44 patients received the CyberKnife treatment, including 2 patients who failed to use gold fiducial markers and were treated with spine tracking instead and 3 patients missing the treatment for other reasons. The numbers of utilized and abandoned gold fiducial markers were recorded for calculation of the utilization and abandonment rates. The reasons for abandonment of gold fiducial markers were analyzed and classified. Results A total of 134 gold fiducial markers were implanted into or pasted to the 44 patients. In all the gold fiducial markers, 111 were utilized and 23 abandoned, yielding a utilization rate of 82.8% and an abandonment rate of 17.2%.The reasons for abandonment of gold fiducial markers included large rigidity error (26.1%), unqualified implanted fold fiducial markers (17.4%), displacement of gold fiducial markers (26.1%), and others (30.4%). Conclusions Compared with the CT-guided or ultrasound-guided implantation of gold fiducial markers, the CT-guided 3D-printing coplanar or non-coplanar template assisted implantation of gold fiducial markers requires only two puncture needles for each implantation and implants two gold fiducial markers by a single needle, which reduces the number of puncture needles, risk of puncture-induced injury, and incidence of complications after implantation. Not all the gold fiducial markers implanted by a variety of ways will be utilized. Some gold fiducial markers will be abandoned for different reasons, which should be taken into account during implantation of gold fiducial markers.

Key words： Neoplasms/stereotactic radiotherapy CyberKnife Fiducial markers Qualified rate

收稿日期: 2017-12-27

通讯作者: 王俊杰,Email:junjiewang_edu@sina.cn

引用本文:

徐飞,郭福新,彭冉等. 射波刀立体定向放疗中金标利用率统计与弃用原因分析[J]. 中华放射肿瘤学杂志, 2018, 27(3): 295-298.

Xu Fei,Guo Fuxin,Peng Ran et al. Utilization rate of gold fiducial markers and reasons for abandonment in CyberKnife stereotactic body radiation therapy[J]. Chinese Journal of Radiation Oncology, 2018, 27(3): 295-298.

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http://journal12.magtechjournal.com/Jweb_fszlx/CN/10.3760/cma.j.issn.1004-4221.2018.03.013 或 http://journal12.magtechjournal.com/Jweb_fszlx/CN/Y2018/V27/I3/295

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